ccbe1

Gene

Ccbe1

Protein

Collagen and calcium-binding EGF domain-containing protein 1

Organism

Mus musculus

Length

408 amino acids

Function

Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.

Similarity

Belongs to the CCBE1 family.

Mass

44.357 kDa

Sequence

MVPPPLPSRGGAAKRQLGKSLGPLLLLLALGHTWTYREEPEDRDREVCSENKITTTKYPCLKSSGELTTCFRKKCCKGYKFVLGQCIPEDYDICAQAPCEQQCTDNFGRVLCTCYPGYRYDRERHQKRERPYCLDIDECATSNTTLCAHICINTMGSYHCECREGYILEDDGRTCTRGDKYPNDTGHEEKSENEVKAGTCCATCKEFSQMKQTVLQLKQKMALLPNNAAELGKYVNGDKVLASNAYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRHGSKGERGAPGPPGSPGPPGSFDFLLLVLADIRNDIAELQEKVFGHRTHSSAEDFPLPQEFSSYPETLDFGSGDDYSRRTEARDPEAPRNFYP

Protein

Collagen and calcium-binding EGF domain-containing protein 1: Ccbe1

Gene

CCBE1

Protein

Collagen and calcium-binding EGF domain-containing protein 1

Organism

Homo sapiens

Length

406 amino acids

Function

Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.

Similarity

Belongs to the CCBE1 family.

Mass

44.103 kDa

Sequence

MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCLKSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYDRERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKYPNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHRTHSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP

Protein

Collagen and calcium-binding EGF domain-containing protein 1: CCBE1

Gene

ccbe1

Protein

Collagen and calcium-binding EGF domain-containing protein 1

Organism

Danio rerio

Length

401 amino acids

Function

Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways.

Similarity

Belongs to the CCBE1 family.

Mass

43.849 kDa

Sequence

MIYPGRGASLSVAVALVLFSSGAPWTFREEKEDVDREVCSESKIATTKYPCVKSTGEVTTCYRKKCCEGFKFVLGQCIPEDYDVCAGAPCEQQCTDHFGRVVCTCYDGYRYDRERHRNREKPYCLDIDECANNNETVCSQMCVNTPGSYRCDCHSGFYLEDDGKTCTKGERAPLFEKSDNVMKEGTCSATCEDFHQMKMTVLQLKQKMSLLSSNTEINKQMTNEKMMMTTNSFLPGPPGPPGPAGTPGAKGSSGSPGQMGPPGLPGPRGDMGPIGPSPDLSHIKQGRRGPVGPPGAPGRDGMKGERGFPGPSGPPGPPGSFDFLLLMMADIRNDIAELQSKVFSRPLHSSFEDFPSAPDSWRDTPENLDFGSGEDYKSQSPPKSSRKRKLPRNLKNPDWPV

Protein

Collagen and calcium-binding EGF domain-containing protein 1: ccbe1