Protein
Sirohydrochlorin cobaltochelatase CbiKC
Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Function
Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme.
Similarity
Belongs to the CbiK family.
Sequence
MVPPRWGSLDSLKPQQHLPMTKKGILLAAFGSGNRQGESTLRLFDERVRERFPGVPVRWAFTSVIMRRRLAAARKKTDSVLKALQKMWFEKYTHVAVQSLHIIPGAEYGDLVADVEAMRRDDGFTAATVGAPLLAGSGDMERSAAALLAHLPAGRKPDEAVVFMGHGTRHPAESSYEALAALVRRVDPHVHIGTMGGSRTLDHILPELQQGGVKGVWLMPLLSVVGRHATEDMAGTDPESWKSRLEASGLRCIPVLRGTAEYEGFVDIWLDHLTAAVSALDD