Protein
Citrate (Re)-synthase
Organism
Dehalococcoides mccartyi (strain CBDB1)
Function
Catalyzes the condensation of the acetyl group of acetyl coenzyme A (acetyl-CoA) with oxaloacetate to form citrate. This enzyme is highly Re-face stereospecific with respect to the C-2 of oxaloacetate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Sequence
MGKIFIIDVTNRDGVQTARLGLSKLEKTLINIYLDEMGIFQSEFGFPTTKHERGYVEANLELAKMGVIKNLRLEGWIRAIVADVDLAFRRAPSLKHLNLSISTSEQMINGKFQGRKVFKDIIEDMTIAVNAAYAKGAETVGVNAEDASRTSIVNLIEFGKAAKEVGATRLRYCDTLGYDNPFTIYETARTLAEKVGMPIEIHCHGDLGMAIGNSLAGAKGVIDGGQDVYVNTTVNGIGERAGNADLVAFLLAILKSKGFGEKYQLGHEVDLSKAWKIARFASYAFDVEIPINQPGVGRNCFAHASGIHADGVIKDSQNYELYGYEELGRGEALMVETGREICAGQYSGISGFRHVMGNMSVELPEDKDEANKILELVRYANVEAHKPLVEDELIFIAKYPEISRRLLTLTPLMND