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cas6b

Gene
cas6b
Protein
CRISPR-associated endoribonuclease Cas6 2
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
289 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease, generating an 8 base-long tag known as the 5' handle.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas6 family.
Mass
32.637 kDa
Sequence
MPLIFKIGYNVIPLQDVILPTPSSKVLKYLIQSGKLIPSLKDLITSRDKYKPIFISHLGFNQRRIFQTNGNLKTITKGSRLSSIIAFSTQANVLSEVADEGIFETVYGKFHIMIESIEIVEVEKLKEEVEKHMNDNIRVRFVSPTLLSSKVLLPPSLSERYKKIHAGYSTLPSVGLIVAYAYNVYCNLIGKKEVEVRAFKFGILSNALSRIIGYDLHPVTVAIGEDSKGNLRKARGVMGWIEFDIPDERLKRRALNYLLTSSYLGIGRSRGIGFGEIRLEFRKIEEKEG

Gene
cas6b
Protein
CRISPR-associated endoribonuclease Cas6 2
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
241 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This protein processes pre-crRNA into individual crRNA units.
Similarity
Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
Mass
28.84 kDa
Sequence
MRLKLSLTPKQDFSFDKINKHTIQGFIYSLLKDTEFGEMHNQPRFKFWCFSDIFPPNDFVKGEDKYLLISSPREEFINVLYERLDNLEEVNLNNFKFEVSELKKFDLKVKNKFITGSPIVLYKDKDRGEYIKFYDDDFDLMFFVQRLQDNAVKKYKAFYNEEPVLNGFIFDRISPRVRNGRVDVYVRIAKKGREFLVVGTTWKLLEKIKIRKEERKFYKFIMDCGLGEKNSLGFGFINPIK

Gene
cas6b
Protein
Putative CRISPR-associated endoribonuclease-like protein Cas6
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
241 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), also called psiRNA (prokaryotic silencing) in this organism (Potential).
Similarity
Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
Mass
28.046 kDa
Sequence
MRIEIKLLPLQDNPVIPFNYNYELYSQIVEKAGAIEPRIVKLLESPHGYWTFSRIIIRKREIIPEKGIKILSDDISLYISSSNKEIIKGIVEGIEKSPEFKIGDVGFLVADIKALKSKEIKNVNIFSTLSPIVVRTVKFEGDKLKHWDLYPHDELFLDRLRKVMLLRYHEVMGDLPEDKDFRIELIKFKPTRLIVKDSYIRGSLMVFRYYGSKEIAKFGYENGFGEKTNLGFGMVKIIEEQ