CAS5

Cell wall integrity transcriptional regulator CAS5

821 amino acids

Transcription factor involved in the cell wall damage response. Acts with ADA2 to promote cell wall integrity. Required for expression of numerous cell wall biosynthesis inhibitor caspofungin-responsive genes. Plays a key role in adherence, hyphal development, and virulence.

92.784 kDa

MENYLLSSPTQLSQPYDDGTNSLLFMDNYELSQNLSQPLDQHLQSLQQQSQVQSQAPQQVQSLNQHQQLPQIQPFPTLVNNQQYAQETFQQLSQQHQQQQQQQQQFSPFQQSQLQQQFQYQYSQQQQQQHFQQPVTIEEEIVPASNNTNIQISKFFDDNKGDDEDIANSGNFNEFDHSRNISLDDTTITDLHRRENSINPPTGLPHSISSNTIYSYSSFESPQSHIQSQPSYSQGYHNQNSLSTPLRRNKSYSISSANFNQSPVNLATTAMNKIMKTPLRGHTRSRSKVDVNAAVTAAMNLGQATKSNSTSSYNSTLNPFYTPSQQLSSTDDDDISTPLLTPGTKLHTSKSTFFSPYNKDDLEDQDDDAVKQLRKAKSYTSLLRKKKREDMTPSKQNQQHQQQQQQQQQQQQSRQSGGGHIQNLSFPNSTSQPKIDLLAYDQNPMTSYPPMDKSILKNLNQSISPFNKPKLSPPPSNFPSISIDLTTIATNKSSSFSSSTTHRNYNENTPFNSANSTSGGLLPPMATFTVPTVIKEELQVHNLQEEEQEHQDEQMEIDSFESNEKNARPTLSTSSLVRSMKMANLEISNDQQMSSNEDENIVTEAVVKQEKNGPVVDDVNGTGTNSKKPRKKQKSKSKENCNKKGKVATGNGKDNDKNNECLVNKGNKTNNNDTSNDKLDNDNKNTNGNGNNDNDNDSEENNDNVDDADDDDDGTVTIPIPEDLNVTKVKVRNNRSKSNDKSDPKKKHKCPICESRFQRPEHVKRHLKSHSSEKPFECQMPNCGKRFNRKDNLKAHLKKIHGLVKGQEEFTRVLNENKEVS

cas5

CRISPR-associated protein Cas5

265 amino acids

CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Plasmid targeted by CRISPR locus P1 transform wild-type cells very poorly (PubMed:22767603). This protein helps process or stabilize pre-crRNA into individual crRNA units, in vivo Cas5 and Cas6 are also required for optimal crRNA processing and/or stability (PubMed:24459147).

29.323 kDa

MSPHIDANGVPIDCLSFTVRSTWGHFKRVGRSVTKQTYRIPPRTTVAGMLAAIVGADRDSYYDVFGADNSAIAITPLSDLRTVNIPTTGLGTDPKQDVTETAGSWRTYKLTYQNTTGDRQLHSYEVLADPAYRIDVALENEEFYDSLREHLVNGTSIYPPSLGKSEYLAVIEDVEVDREPEVQDIDETLDIDSVVPISLSEAVPQGKVTYGVERSPAVMVRESGGRRTTRFDDYVYAQQASNPVRIGEQTDVAPVQVGDRTVVFR

cas5

CRISPR-associated protein Cas5

245 amino acids

CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).

Belongs to the CRISPR-associated protein Cas5 family. Subtype I-A/Apern subfamily.

28.255 kDa

MIMEALVALLRFPFYSFGKQSYQVRQSLLLPSPSALKGALAKGIILLGGKKGKSLDEIAKKTVEELENKLIYVGAKPYKSSIIKTPILLKRLRNLEDQKNPEKSDAMRREYVFAREILAIYVFRRKLSEEEKDLMLKAVYLIDQLGDTECVGNVIKTEWVEVKEEKAPLKTYVKFKKVSKMSINGGIIENMLETPNFGNKVKEEPYLLPLIEKRYRRSSYYVESDRIFDGNYKIIAFDEVIGLWI

cas5

CRISPR-associated protein Cas5

228 amino acids

CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).

Belongs to the CRISPR-associated protein Cas5 family.

26.199 kDa

MQWVKLTLHFPSFFSYRIPDYSSQYALSVPLPSPSAIKLSLVATAIRTTGNVAEGERVFYAVRDADIRILPPEQIAINSVLIKRLKKKKNPTELETFEKTFGVREYVFFPDDVNLFIGCDDIDIAIKYFGMLRYLGSSDSMLYVKCIEKINEPPKSAIKAIADKEFAEAISKEPYIVYPVKDISKKAKFEQINPYSGKSGRNVFERKYYLIKARIKKGKKWKLLEIQC