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cas2

Gene
cas2
Protein
CRISPR-associated endonuclease Cas1/endonuclease Cas2 fusion
Organism
Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1)
Length
264 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
Similarity
In the C-terminal section; belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
28.671 kDa
Sequence
MDEVLLLTGGISITTRALRALLATGATVAVFSPRGEPLGIFMRPVGDATGAKRRCQYKAAEDGRGLQYAKSWVFKKILGQRDNIKAWRRRLRGYSQYAESLAKALPGAGLHGAMETPRRRRRGQDGGQAGVRGRPTHPPVPPGAGRRSPGGAPRGQEASLRRDPQRGQSSGALHMYVIVVYDITENDVRAKVADILRAYGLARIQRSAYVGRLPPALVKELAERLARAVRGANADIAIFKVDKRTIDTSLRIPPRPPAGHVALH

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Length
143 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
16.854 kDa
Sequence
MIEDKFMRVLLMFDVPTKSKKEQKLASKFRNNLIKLGYFMLQFSVYMRICKGLSSAKSSIENVKKILPPYGNVRALIITEKQFDKMELLLGGIVFNEKVNNETNLTLFDIDSHGEFKYKNSNNEEIQINKKQEKYHQQNLFEF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Streptococcus thermophilus
Length
114 amino acids
Function
When the CRISPR3/cas system consisting of cas9-cas1-cas2-csn2-CRISPR3 or just cas9-CRISPR3 is expressed in E.coli it prevents plasmids homologous to spacers 1 or 2 from transforming.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
13.413 kDa
Sequence
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNHTANTAMVGRLKANNPKKGNITILTVTEKQFARMIYLYGDKNTSIANSEERLVFLGDNYCDED

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
113 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRNA is required for all activities (Probable). This CRISPR-Cas system protects bacteria against transformation with plasmids containing DNA homologous to its spacer regions (PubMed:29979631).
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
12.867 kDa
Sequence
MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Streptococcus gallolyticus (strain ATCC 43143 / F-1867)
Length
109 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
12.751 kDa
Sequence
MRMILMFDMPTETAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNSANKAMIDRLQANNPKKGSITLLTVTEKQFARMIYLNGERNTSVANSDRRLVFLGEDYSDEN

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Length
109 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
12.634 kDa
Sequence
MRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNSANTAMIARLKENNPKKGNITLLTVTEKQFARMIYLNGERDTSIANSDSRLVFLGEAFPDET

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Neisseria meningitidis serogroup C (strain 8013)
Length
108 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
12.546 kDa
Sequence
MSEAKFMRIIVFFDLPVITAAKRKAANQFRQFLLKDGYQMLQLSVYSRIVKGRDSLQKHHNRLCANLPQEGSIRCLEITEKQYAAMKLLLGELKTQEKKVNSDQLLLF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Acidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)
Length
108 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
12.428 kDa
Sequence
MLTGYRLMWMVVMFDLPVITKAERKAATGFRNALLDVGFQMSQFSVYLRFCTSQAQVDTLCRQVEQALPAGGKVHIFQFTDKQYERAISFHGRSRQPAQKAPDQFDLF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Streptococcus mutans serotype c (strain NN2025)
Length
107 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
12.346 kDa
Sequence
MILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNSANTAMIARLKENNPKKGNITLLTVTEKQFARMIYLNGERDTSIANSDSRLVFLGEAFPDET

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Desulforudis audaxviator (strain MP104C)
Length
106 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
12.112 kDa
Sequence
MKTLVSYDIVEDKVRRKVFEACKDYGLTNVQYSLFFGDMTHNRREELFQRLRRIIGRQEGKVLICPVCDKDLRLSKAIEVSAGMPEEAAEAAVSYPGRSRKKARAG

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Acidovorax ebreus (strain TPSY)
Length
102 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
11.656 kDa
Sequence
MRMLVFFDLPVVSKADRRAYTVFRRFLLNDGYDMIQFSVYGRILNGTDAAQKHMQRLLANLPSEGSVRVLTVTEKQFASMKLLVGLPLFQEKKVNAAQIALF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Length
102 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
11.843 kDa
Sequence
MYGNDAMLVLISYDVSFEDPGGQRRLRRIAKACQDYGQRVQYSVFECVVDPAQWAKLKHRLLSEMDKEKDCLRFYYLGANWRNKVEHVGAKPAYDPEGPLIL

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
Length
101 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
11.644 kDa
Sequence
MWVIAMFDLPTDTPKARKAYARFRKDLLEDGFTMMQYSVYSRHCASIENAEVHVKRMGAVVPAQGEVRFLTITDNQFGRIKVYVGKKRQPTTQSPSQLQLF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Length
101 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
11.779 kDa
Sequence
MRVIVFFDLPVITPENRHNYSVFRKYLIKSGFIMQQKSVYSKLVLNLTNRDSIVKSIEKNKPPEGLVEVLTVTEKQYAKMEIIIGESKTEYLNTDERLVVL

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Capnocytophaga canimorsus (strain 5)
Length
101 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
12.017 kDa
Sequence
MWVMVLYDLPTETKAMQKAANLFRKRLEDDGFSLFQFSIYLRHCPSRENAEVHKKRVKMMLPKYGKVAVMTITDKQFGDMEIFHSKVREDPPPTYQQLELF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Myxococcus xanthus (strain DK 1622)
Length
97 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
11.589 kDa
Sequence
MAEPRRWYLITYDIRDPKRWRKVHALLKGYGEWLQLSVFRCSLTDRDREKLRWELSRRMDAVDTLLVIGLCGGCVERVRAINAKEDWPEEPAPFKVL

Gene
cas2
Protein
CRISPR-associated endonuclease Cas2
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
96 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Involved in the integration of spacer DNA into the CRISPR cassette (By similarity). Functions as a dsDNA-specific endonuclease, acting on circular and linear DNA; has no activity on ssRNA or ssDNA.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
10.881 kDa
Sequence
MLVLITYDVQTSSMGGTKRLRKVAKACQNYGQRVQNSVFECIVDSTQLTSLKLELTSLIDEEKDSLRIYRLGNNYKTKVEHIGAKPSIDLEDPLIF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
96 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
11.214 kDa
Sequence
MLVLVTYDVNTETPAGRRRLRRIAKTCQNYGQRVQFSVFECNVDPAQWVKLRSKLLNEMDPKLDSLRFYFLGSNWQGRVEHEGAKEPRDLEGTLIL

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
94 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
11.114 kDa
Sequence
MRELYLVIAYDTPDDRRRARLAKLLKGFGERRQYSVFEARLTREQWAHLKGKLEALVNKEEDVLAVYFLPPEAVGRTWRIGHEGLKRLEDPDFV

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)
Length
94 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
10.744 kDa
Sequence
MSSRLAVFAYDIRDDRVRRHALKTLREWRLDGQLSVHECQVDAIQARRLFEQLGDELDPATDAWLFTWVEGHRAVLARGKGRTTALQDGLLLAA

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Thermofilum pendens (strain DSM 2475 / Hrk 5)
Length
93 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
10.861 kDa
Sequence
MIVIVAYDISDEDRRGRLRRYLRRLGLARVNRSVYAGPGTATTAELVAERAKEIVEEGDSVFVIVVREDEYQRAHVFDGRDYYIVSERKYEVY

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Length
92 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
10.049 kDa
Sequence
MVYVLIAYDISNDSKRLKAAQKLLQMGFARVQKSVYIAKGGRSLAKEAYRALQRLADSGKDKIMVMVIPGDSVRDAYGLGGSLEDGKRVVVV

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Nanoarchaeum equitans (strain Kin4-M)
Length
91 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
10.915 kDa
Sequence
MQYKINMYAIVVYDVNVSRQNQIREFLRKYLYHVQRSVFEGEISPSSLYYMKKILQSYIGETDSLIIYVLRDKSCLMDKIVLGEDKDLQIY

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Length
87 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Involved in the integration of spacer DNA into the CRISPR cassette (By similarity). Functions as a ssRNA-specific endoribonuclease.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
10.238 kDa
Sequence
MYVIMVYDVNEKRVAKILKIARKYLKWVQNSVLEGELSPGKYEKLKLEVSRLIDEKEDSVRFYVMDSQKVFNLETLGVEKGEDGFIF

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Dictyoglomus turgidum (strain Z-1310 / DSM 6724)
Length
87 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
10.602 kDa
Sequence
MYVIMVYDVNQRRINKVLNTARKYLEWIQNSVLEGEITEAKFEMLKREIEIIINEEEDSVIFYIMRTTKYSERQILGIEKNKREQIL

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
85 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
9.979 kDa
Sequence
MYIVVVYDVGVERVNKVKKFLRMHLNWVQNSVFEGEVTLAEFERIKEGLKKIIDENSDSVIIYKLRSMPPRETLGIEKNPIEEII

Gene
cas2
Protein
CRISPR-associated endoribonuclease Cas2
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
85 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Mass
9.919 kDa
Sequence
MYIIVVYDVSVERVNRVKKFLRQHLHWVQNSVFEGEVTLAEFERIKAGIGELIDGDEDSVVIYKLRSMPKREVMGVEKNPIEDII