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cas1-1

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
352 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
41.079 kDa
Sequence
MVHKVSQREFSRCYKRNCDCICRKPKQRRNVYLNYSLELLITIFKEVIPNLPMDKKIAFVKDYGAYLKVEKGLITCKIKNQVKWSIAPTELHSIVVLTNSSISSEVVKVANEYGIEIVFFNKHEPYAKLIPAKYAGSFKVWLKQLTAWKRRKVEFAKAFIYGKVHNQWVTLRYYERKYGYNLTSQELDRLAREITFVNTAEEVMQKEAEAAKVYWRGVKSLLPKSLGFKGRMKRVSDNLDPFNRALNIGYGMLRKVVWGAVISVGLNPYIGFLHKFRSGRISLVFDLMEEFRSPFVDRKLIGLARESADKVTDLKTVYSLFSDVKEDEIYTQARRLVNAILNDEEYRPYLAK

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
345 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Involved in the integration of spacer DNA into the CRISPR cassette (By similarity). Acts as a dsDNA and ssRNA nuclease, binds to linear and circular dsDNA and linear ssRNA and ssDNA.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
39.046 kDa
Sequence
MRLVVDGFGKYLGIENGLIVVKEKGKALRKVRPEDLKQVLIIGKAAISSDAIKLLLKNRVDVVFLDFNGEILGRLSHPLIGTAKTRREQYLAYGDKRGVHLAKEFIKAKMANQMAILTNLAKARKDSNPEVAESLLKAKKEIDACLNELDGVEAEMIDKVRERLLGIEGKASKHYWDAISLVIPEEYRFNGRRGIEIGSPRYAKDIVNAMLNYGYSILLAECVKAVELAGLDPYAGFLHVDVSGRSSLAIDLMENFRQQVVDRVVLRLISYRQIKPEDCEKRNMVCQLSDNARRLLLASLLERLDSKTQYRGRNLAYSSIILLHARDVVAFLRGERRYEGFVQKW

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
343 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
38.756 kDa
Sequence
MKKHLNTLFVTTQGSYLSKEGECVLISIDRVEKTRIPLHMLNGIVCFGQVSCSPFLLGHCAQLGVAVTFLTEHGRFLCQMQGPVKGNILLRRAQYRMADNYDQTATLARLFVIGKIGNARVTLARALRDHPEKTDGEKLKNAQHVLAGCIRRLQEATDQELIRGIEGEAAKAYFSVFDECITADDPAFRFEGRSRRPPLDRVNCLLSFVYTLMTHDIRSALESCGLDPAAGFLHKDRPGRPSLALDMLEEFRSYIGDRLVLSLINRGQIHAKDFDISETGAVAMKDDARKTLITAYQQRKQEEIEHPFVGEKMAVGLLWHMQAMLLARYIRGDIDMYPPFVWR

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Length
343 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
39.065 kDa
Sequence
MHILLNTLYLMTPRTLVRLDHETVKIEVEGELKMQIPLHHLGSIVCFGDVTLTTPLIMRCAEDKRLIVFHDQHGRFKARVEGPVSGNVFLRHAQHEALSDSKKTTAIARNIVAGKIRNTRQVVLRGAREADNEDDRKALQETARELAHGLDALSRSPDLEQIRGIEGNAARHYFATLDRMVRVNREAFKITHRNRRPPLDRMNALLSYIYALLLNDCLSAAEGVGLDPQIGYLHVLRSGRPALALDLMEEFRAILADRLALTLVNRRQIDERDFVERPGGAVHINDNARKEIAIAYQKRKQEEVLHPVLNRKVPLGLVPHIQARLLARVLRGDAEEYLPFMYR

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Length
331 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
36.741 kDa
Sequence
MNSVLITGAGYRIRKRGDVLTIETGKDSDTAEPPRTLSPLGLDLLAIAGDHSISTAAVRLVTSHGGAIALMDGLGNPFGHFLPLGRSALIEQYEAQASAPEERRLEIARSICTGALENKRTLLSNLERIRGFDLSREIRLVEDAQDKALECQSLDSLRGVEGSGAHAYFQGFSLAFDEEWGFLGRSQNPATDPVNSLLSYGYGMLYIQARQALVLSGYSPYYGAYHETYKKQEALVYDLVEEFRQPVVDRTVVTFLAKHMATPDDFTYPDEGGCMIGTMAKKKYAAAVLTRIHGKVKYEEQTFQDIFKRQAERIGKALTEGDEYVPYRYRT

Gene
cas1-1
Protein
CRISPR-associated protein Cas1 1
Organism
Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1)
Length
322 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
37.88 kDa
Sequence
MSKKNYYLLSEGILKRKENTIYFVNEKGSKPLPINKIYSMYAYGQITISSQVISLFAKEGIPIHFFNYYGYYNGSFYPRESLLSGDLLIKQAEHNIDFSKRLKLAKLFVEGAAKNILKVLAYYKIENNIKNTLTELNESSKITEVMNVEGRIRAEYYQYFDDILPDEFKMEGRSRQPPTNMINSLISFGNSMMYASVITELYNTQLNPTISYLHEPAERRFSLALDLSEIFKPIIVDRVIFYLVNKKMITEKDFNQDLNCCLLNDKGRATFVKEYNKRLETTIKHKDLGRKVSYQRLIRLEAYKLKKHVFGMKEYDPFVIWW

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Length
318 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
36.548 kDa
Sequence
MSTVFIDRKDIEIRVDGNSISFYAKGKKDGSLPLSPLKRVVIVGNVKIETSVLYKLVNHGITVLFLTGKLKYSGILNGPLHNNGLLRVKQYQKSLSGFSLKFAKELIKRKIVSQRDFLSEIREIKKALAMQADRAIEILNKAISNIEVTPISIDSLRGIEGAASSIYFITYSKIFPNSLKFVRRIKRPPKDPVNAMLSLCYTLLHYEIVREIQLIGLDPTIGFYHQFEYGRESLACDLVELFRVNVDRFVYELFKAKHLGNRDFMKDEESGGVYLKKTGRKKFYPLYEQWVQQQRTIWRGEVQGFARRILEEKDIISG

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Length
318 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
36.548 kDa
Sequence
MSTVFIDRKDIEIRVDGNSISFYAKGKKDGSLPLSPLKRVVIVGNVKIETSVLYKLVNHGITVLFLTGKLKYSGILNGPLHNNGLLRVKQYQKSLSGFSLKFAKELIKRKIVSQRDFLSEIREIKKALAMQADRAIEILNKAISNIEVTPISIDSLRGIEGAASSIYFITYSKIFPNSLKFVRRIKRPPKDPVNAMLSLCYTLLHYEIVREIQLIGLDPTIGFYHQFEYGRESLACDLVELFRVNVDRFVYELFKAKHLGNRDFMKDEESGGVYLKKTGRKKFYPLYEQWVQQQRTIWRGEVQGFARRILEEKDIISG

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Francisella tularensis subsp. novicida (strain U112)
Length
318 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
36.558 kDa
Sequence
MKHLIISEYGIYLGLESGRLVVKNKDDKKYFPLNRLATLSIAKKGVSFSSDLVEQFSLRGIKLFFLDFRGVAHSMLVGANQHAVVQARINQYRYIDRNALTLSIKLIAAKIKNQRATLNYFNKHHKSINLLNAIEELKRVAQLIKNAKTLNDVLGYEGYAANIYFSSLAKDKFLSASFANREGRGSQEIANSMLNFGYAILSSYILNAITNAGLEPYLGFLHQKRPGKMSLVLDLMEEYRAWVVDRVVIKLREQYKNKQYIDTKLKSILISEIQATIAKKYIYNGKKLKLEHIIQRQVYRLSGEFAGEHNYKPYIFKW

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
315 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
34.819 kDa
Sequence
MTLHLTRQGATLRLRQGRLLLEEEGREVAGFPARQVRSVALWGNVRLSTPALVFLLRQGVPVFFYSLEGFLHGVAGAYPDPHPAHLRAQFAAEGLPLARAFVVGKLRSALALLERHRLPEAGGVVEALARAEGASELERLRGAEGEGSRVYFQGLARLLGPYGFGGRTRRPPRDPVNAALSYGYALLLGRVLVAVRLAGLHPEVGFLHAEGRRSPALALDLMEEFRVPVVDQVVLSAFRRGLLTPSHAEVREGGVYLNEEGRRRLIQLFEERLLEGVSHPLGFRKPLGETIEVQAQRLKAALLGRGRYTPFYLWR

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Length
313 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
34.305 kDa
Sequence
MADPAFVPLRPIAIKDRSSIVFLQRGQLDVVDGAFVLIDQEGVRVQIPVGGLACLMLEPGTRITHAAIVLCARVGCLVIWVGERGTRLYAAGQPGGARADRLLFQARNALDETARLNVVREMYRRRFDDDPPARRSVDQLRGMEGVRVREIYRLLAKKYAVDWNARRYDHNDWDGADIPNRCLSAATACLYGLCEAAILAAGYAPAIGFLHRGKPQSFVYDVADLYKVETVVPTAFSIAAKIAAGKGDDSPPERQVRIACRDQFRKSGLLEKIIPDIEEILRAGGLEPPLDAPEAVDPVIPPEEPSGDDGHRG

Gene
cas1-1
Protein
CRISPR-associated endonuclease Cas1 1
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Length
302 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Mass
33.382 kDa
Sequence
MEVVVKDWGVSLGYSRGALVIKKRGGVDRIPLFQVDRIWILTGGVSISSRLVRALSHHFIDVVFFDAKGNPVARLFPPEANGTVTHRRAQYEAYLTGRGFELAKLVTYGKLINQARALRRLGQWKREHYGALAEAASKIADLAGRIPSCADVQCVLGHEGAAASLYWDAVSKTTGLPGRNPEAADPLNLALNYGYGVLKYAVWRQAVIHGLDPYAGYIHADKSGRPSLVLDLMEEFRPHVDLLVIRLRPSADWADGGVLKREIRAMLVEEWTGERLEPVIARQVGLAVAHLHGQRAYTPHQL