Protein
Cullin-associated NEDD8-dissociated protein 1, N-terminal part
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Function
Assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor when interacting with candA-C (By similarity).
Sequence
MGDRHTIQQNLNGLLSKLNDPDPDMRYMSLNDLYGILSNPCSSYLAHDQASATRLAEGLLKALDDQHGDVQNQALKCLGPLVARLPLEGLRTLLERLSNLTTSQTIDTSVPNTALRVIVTALPRPQPNQAPSPDANMAYSAVSEVLIPRLIGPGPHKRRGSVTKGMLEKDPAKGFSSDAIDVLIQVASCFGALLQESELTALEKAVMSIIDNDTAGTVVTKRALAAISALVVYFSDEQFGILVSELVERFNSPQLSTVHRRHLIAAVGCLARTVPAKFGPHLSTLAPFIFSAVGEDNLEVSHVLHYLCTSASNVYSSRNKPKIYHQYRQLPKEKLITGM