Protein
Serine/threonine-protein phosphatase 2B catalytic subunit
Organism
Dictyostelium discoideum
Function
Catalytic subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals.
Similarity
Belongs to the PPP phosphatase family. PP-2B subfamily.
Sequence
MSTNNNKAPTSQSSDKSATTESKLNDNENTETETKTDENNEEKPKMTLKPPQPKIENKVSTIDRVVPSVKYPKSLPLPHDVLFNEDKTINLPKLQEHFFAEGRLNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENDIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFSPEIREHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNDATGFPSVITLFSAPNYLDAYNNKGAVLRYENNVMNIRQFTCSPHPYWLPNFMDVFTWSMPFVSEKVAEMLLVLLNLCNDEEAEKNENAQTVKDTSEEEKRRQMLRAKVKSVSKMMRMFSLLRQERETIMMIKSFSPSRKIPQGLLTEGKDALKKALGDFAQARKMDLINEKRPPILDRVNSRGELLRMNSRGELFRINSKGDLFRSNSYADLKPPQGPQETIKITECHEQNITTNNINPNSITTNENNSNEQLQQQQQQQQQQQPPTTTSTTTQTEVAK