cact

NF-kappa-B inhibitor cactus

500 amino acids

Involved in the formation of the dorsoventral pattern. It inhibits nuclear translocation of the dorsal morphogen in the dorsal region of the embryo. Acts as a negative regulator of the NF-kappa-B (rel) signaling pathway. Cact is degraded by IKKbeta, this is essential for NF-kappa-B (rel) activation.

Belongs to the NF-kappa-B inhibitor family.

53.818 kDa

MPSPTKAAEAATKATATSDCSCSAASVEQRAPSNAANPSSSLATSGKIGGKTQDQTAAINKQKEFAVPNETSDSGFISGPQSSQIFSEEIVPDSEEQDKDQQESAPQKEQPVVLDSGIIDEEEDQEEQEKEEEHQDTTTATADSMRLKHSADTGIPQWTVESHLVSRGEQLNNLGQSSSTQITGRSKVQSSTASTANANPSGSGATSSAPPSSINIMNAWEQFYQQNDDGDTPLHLACISGSVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGATEIHEAHRQYGHRSNDKAVSSLSYACLPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNEDLANFLLDECEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAETVTPPDSDYDSSDIEDLDDTKMYDRFGDPRYFVSYNGGNPMTVA

cact

NF-kappa-B inhibitor cactus

489 amino acids

Involved in the formation of the dorsoventral pattern. It inhibits nuclear translocation of the dorsal morphogen in the dorsal region of the embryo.

52.539 kDa

MPSPTKAAEAATKATATSDCSCSAASVEERGPVNAANPSSTXATSGKIGGKTQDQTAAINKPKEFAVPNETSDSGFISGPQSSQICSEEIVPDSEEQDKNQQQSAPQKEQPVVLDSGIIDEEEEHQDTTTATADSMRLKHSADTGIPQWTVESHLVNRGEQLNNLGQSSSTQITGRSKFQSSTASTANANPSGXGATSSAPPSSINIXNAWEQFYQQNDDGDTPXHLACISGSVEVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGAEVRDRHGNTALHLSCIAGEKQCVRALTEEFGATEIHEAHRQYGHRSNDKAVSSLSFARLPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNEDLANFLLDECEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAETVTPPDSDYDSSDIEDLDDTKMYDRFGDPRYFVSYNGGNPMTVA