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cII

Gene
cII
Protein
Protein cII
Organism
Enterobacteria phage P4
Length
264 amino acids
Function
Mutations in this gene cause a clear-plaque phenotype as a result of efficient killing of infected cells by P4. How this comes about is not understood.
Mass
30.169 kDa
Sequence
MAELLREQEVKIALIEWLYKKGMLSDATIINEMVVANWSRRADLAIANGSLQAFEIKSDFDSLKRLDGQLKIFKSSFEKVTIVCAPKFTSEVSKRVSSDVGVVEFQSNNSSVRFKIIQKGRVCSRLNKFVYLGFLLKSELKDLLNQYGITFSNELHRDCLEVLASKLSLNKIREFVITSIKNRYHATSNDFLSRLHGNQEISINDLALLSKAKRRNNSLVKFEFKACSEKSLNEYHKVDVDSIVRKYGDDVSYIPEKVLKRVVG

Gene
CII
Protein
Regulatory protein CII
Organism
Escherichia phage 186
Length
169 amino acids
Function
Involved in the establishment of lysogeny.
Mass
18.692 kDa
Sequence
MFDFQVSKHPHYDEACRAFAQRHNMAKLAERAGMNVQTLRNKLNPEQPHQFTPPELWLLTDLTEDSTLVDGFLAQIHCLPCVPVNELAKDKLQSYVMRAMSELGELASGAVSDERLTTARKHNMIESVNSGIRMLSLSALALHARLQTNPAMSSVVDTMSGIGASFGLI

Gene
CII
Protein
Regulatory protein CII
Organism
Enterobacteria phage phi80
Length
132 amino acids
Function
May be involved in activation of synthesis of the CI protein.
Mass
14.908 kDa
Sequence
MSALIINEYREQGGTAISFPEDISRARQKLFRFLDNRFDSDQYRENVRELTPAIMAVLPVEFRTRLAPQNDTMSLIASAMKECSEAKQAVLLNAPEHQKMKEVSEGIASLFRLMPEQVGPLMTMVTSMLGVI

Gene
cII
Protein
Transcriptional activator II
Organism
Escherichia phage lambda
Length
97 amino acids
Function
Acts as a transcriptional activator that allows virus to initiate a latent state. Following infection, participates together with cIII in activation of the Pe and Pi promoters, which are responsible for the transcription of the cI (repressor) and int (integrase) genes, respectively. Both of these gene products are required for the establishment of latency.
Similarity
Belongs to the lambda phage cII protein family.
Mass
11.056 kDa
Sequence
MVRANKRNEALRIESALLNKIAMLGTEKTAEAVGVDKSQISRWKRDWIPKFSMLLAVLEWGVVDDDMARLARQVAAILTNKKRPAATERSEQIQMEF

Gene
CII
Protein
Regulatory protein CII
Organism
Enterobacteria phage 434
Length
97 amino acids
Function
This protein and protein CIII form a complex that is involved in the initiation of lysogeny. The complex binds at either of the cy regulatory sites preceding the CI repressor protein and integrase coding regions and induces transcription of these genes.
Similarity
Belongs to the lambda phage CII protein family.
Mass
11.072 kDa
Sequence
MVRANKRNEALRIESALLNKIAMLGTEKTAEAVGVDKSQISRWKRDWIPKFSMLLAVLEWGVVDDDMARLARQVASILTNKKRPAATERSEQIQMEF