About Products Protein Database Contact

btrW

Gene
btrW
Protein
Serine/threonine-protein kinase BtrW
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Length
142 amino acids
Function
Possible negative regulator of sigma-B activity (By similarity). Phosphorylates and inactivates its specific antagonist protein, BtrV. Upon phosphorylation of BtrV, BtrW is released and binds to an unknown partner(s) that might be sigma-B, thereby blocking its ability to form a complex with its partner (possibly an RNA polymerase holoenzyme (E-sigma-B)). Involved in type III secretion system (TTSS). Phosphorylates BtrV.
Similarity
Belongs to the anti-sigma-factor family.
Mass
15.804 kDa
Sequence
MSSKTDTLELSVTATTATDALYWLEHIALRDRWSARLRFTLTLCADEALNNIVSHAFTPGHPAAIHLTLRQTRREVSLHIADNGAAYDPTQALSPPLARSLDDAQPGGHGLRLMRHFMHALSYQRRDGWNHLTLTSHSAPES