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btrV

Gene
btrV
Protein
Putative anti-sigma factor antagonist BtrV
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Length
116 amino acids
Function
Possible positive regulator of sigma-B activity (By similarity). Non-phosphorylated BtrV binds to BtrW, preventing its association with an unknown partner(s) that might be sigma-B. When phosphorylated, releases BtrW, which is then free to complex with and inactivate its partner. Involved in type III secretion system (TTSS).
Similarity
Belongs to the anti-sigma-factor antagonist family.
Mass
12.634 kDa
Sequence
MKLTMDKIDGMLIACLQGVVNSANAEQLEAELAAQVDKGERRVVLDLGRLDYISSAGLRVVLLVAKQLRQVQGELVLCELKPHVREVFEISGFLSIFPVANSREAAAAAFKTALPR

Gene
btrV
Protein
4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase BtrO
Organism
Bacillus circulans
Length
82 amino acids
Function
NAD(P)H:FMN oxidoreductase component of a two-component system involved in the biosynthesis of the side chain of the aminoglycoside antibiotics in the biosynthetic pathway of butirosin. Together with BtrO, mediates hydroxylation of gamma-L-Glu-GABA-S-BtrI.
Mass
9.416 kDa
Sequence
MDNKERNTLYQVVYAISGVTGEDGDELVETFKQGPMEVDKRDFFEIVQRVESLFDCTLDMNLEGPYLIHADEIVTKITKLNV