btbd6b

Gene

btbd6b

Protein

BTB/POZ domain-containing protein 6-B

Organism

Danio rerio

Length

482 amino acids

Function

Adapter protein for the cul3 E3 ubiquitin-protein ligase complex. Promotes the export of zbtb16/plzf from the nucleus to the cytoplasm and targets zbtb16/plzf for ubiquitination and degradation. Up-regulates neurog1 expression and antagonizes zbtb16/plzf, to promote neurogenesis (By similarity).

Mass

53.273 kDa

Sequence

MAAELYPASINTNLPNSNSTAVTAASKKTIVQVTQTVTTPTTTATQQNINNNNVETASWQSTHPTLRERNALMFNNELMADVHFVVGPPGASQKVPAHKYVLAVGSSVFGAMFYGDLAEGESEIHIPDVEPAAFLILLKYMYSDEIELEADTVLATLYAAKKYIVPALAKACVTFLETSLEAKNACVLLSQSRLFEEPELTLRCWEVIDAQAELALHSEGFCEIDLQTLEIILKRETLNTREAVVFQAALDWAVAECKRQGLGPTARNKRAVLGKALYLVRIPTMTLEEFANGAAQSDVLTLEETHDVFLWYTAANKPKLEFPLQKRKGLTPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDKRIFIAGLGLYGSSGGKAEYSVKIELKRQGVTLAQNLTKFISDGSSNTFSVWFEHPVQVEQDTFYTVSAVLDGNELSYFGQEGMTEVQCGKVTFQFQCSSDSTNGTGVQGGQIPELVFYA

Protein

BTB/POZ domain-containing protein 6-B: btbd6b