Protein
4-hydroxy-2-oxovalerate aldolase 2
Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Function
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
Similarity
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Sequence
MSDIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAASK