bna5-2

Gene

BNA5-2

Protein

Kynureninase 2

Organism

Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)

Length

539 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

57.881 kDa

Sequence

MDTEYQSFVETLRAGQKPEFPAHAKTIEYARELDAHDKLSQLRSDFNIPTKGSLRKKALDGGVAGETKEPRVPNGVSSATKPNGTVNSDLKDDEASIYFVGNSLGAQPKCIRQYIDAHLETWASIGVNGHFTSFDNSPLASWQDMAAACAAQSVDLVGAKSANEIIYMNTLTVNLHLMMASFYRPTAKRHKIIAEWKPFPSDSYALASQLHWHGLAPATSLIEIHPPNPTGSSPPTLTLTTSHILATIDAHADSTALLLLPGIQYYTGQLFDMARITRHARARGIVVGWDLAHAVGNVELELHAWGVDFAVWCTYKYLNAGPGALGGVFVHGRHHSFHRGGGGSGGVGGGRGEGGDGDGGDGGDGDGMALGYRHRLAGWYGADKAVRFEMEKVFWPAEGAAGWQVSNPSVVDLACVRATLGMFERVGMRALRDKAVLLTGYLEWLLLGLLADGVGKGGDGEAAFRIITPGHPADRGSQLSLLLRGGLLEGVSKELADGGVVVDVRKPDVIRVAPVPMYCRFEDVWGFITVFNRALDRCA

Protein

Kynureninase 2: BNA5-2

Gene

BNA5-2

Protein

Kynureninase 2

Organism

Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)

Length

489 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

54.097 kDa

Sequence

MDASAAISQLRQGQKPEWPQNANTSDFAKTLDNSSEFPKTLRHEYVVPTKAQLKRKTLNDDAQTAAKASSSDDEGIYFCGNSLGLQPKAVGEYLNAYLKTWGSIAVGSHFTPMADSPLTPFQDMAAECARRMSDIVGASPSEIVAMNTLTINLHLMMAAFYKPTEKKHKIMCEWRPFPSDWYAIESQIEWHGLDPKKSMLLVKPDDGYLMTTESILKLIDQEADELALIMLPGIQYYSGQLLDIPTITTHARKHGITIGWDLAHAAGNVELKLHDWDVDFACWCTYKYMNAGAGAIAGAFVHSKHGDNGSNVGLKGWYGHDKSSRFLMDNKFVPTPGAQGFQCSNPSAVDLTCLAGSLSVFQKTSVADLRSRSLLLTAYAEHLLTQIASRNIKDGNFPFQIISPLDPRFRGAQLSVLLQEDVMEEVFAGLEENGVICDKRKPGIIRVAPVPMYNTFEDVYKFMHILEGALQPKAEQKTQAHGEAVEARL

Protein

Kynureninase 2: BNA5-2

Gene

bna5-2

Protein

Kynureninase 2

Organism

Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)

Length

474 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

52.467 kDa

Sequence

MSNHVNGVNGVNGVNGVKPVFPENAASKEYAKALDAADPLASFRDKFIIPSKANIQSKRLAKPNISADPCIYFCGNSLGLQPKATAKYMEAHLDTWASIGVNGHFTKIEDSPLDPWWVMAEQAAGSMSKLVGAAPEEVIAMGTLTSNLHLLLASFYKPTATKHKILLDWKAFPSDHYAIESHIAWHDGLDPKKSMVLIGPDEGEYEIPTQKILSIIDEHADEAALILLPGIQYYTGQYFDINTITEYAHSKGLMVGWDLAHAFANVELKLHEWDVDFAVWCTYKYANAGPGSMGGLFVHEKHGKVDYSQGEDSPQFRHRLAGWYGGDRSVRFKMDNKFRPIPGAGGFQLSTSSATDLTCLNASLSIFDQTSISELRRKSVQLTAYLEYLLLKDTTDETRPFRIITPSNPEERGAQLSLLLKPGLLQRVADKLQSASIVCDKREPGVVRVAPAPLYNTYSEVWQFVEQLKAAFQE

Protein

Kynureninase 2: bna5-2

Gene

bna5-2

Protein

Kynureninase 2

Organism

Aspergillus oryzae (strain ATCC 42149 / RIB 40)

Length

468 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.623 kDa

Sequence

MSNVKSSKPVFPENAGSNEYAASLDAADPLASFRDKFIIPSKANINSKKLAKPGLSSDPCIYFCGNSLGIQPKATAKYLEAQLDTWSSIGVSGHFVDLEGSPLKQWQLLSEQAAASMSKIVGAQAEEVAAMGTLTANLHLLLASFYKPTPTKHKILLDWKAFPSDHYAIESHLAWHNLDPKQSMVLIGPDEGEYEISTEKILSYIDEHAESAALILLPGIQYYTGQLFDIQKITAYAQSRDLTVGWDLAHAYGNVELKLHDWDVDFAAWCTYKYGNAGPGAMGGLFVHERHGRVDYSEGEDAPKFRHRLTGWYGGDRSVRFKMDNNFKPIPGAGGWQLSNPSAIDLACLCASLSVFDETSMAELRKKSVMLTAYLEHLLLKDTTDETRPFRIVTPADPEARGAQLSVLLKPGLLQNVSQKLQEGGIVCDKREPGVVRVAPTPLYNTFTDVWKFVSYFKAALDEPELKN

Protein

Kynureninase 2: bna5-2

Gene

bna5-2

Protein

Kynureninase 2

Organism

Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)

Length

464 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.324 kDa

Sequence

MSTTTTSSKPEFPADAATKEYAASLDASDPLAGFREKFIIPSKANIASKKLAKPGLSSEPCIYFCGNSLGIQPKATAKYLEAQLDTWSSIGVSGHFTNVEDSPLREWQNLAEQAAESMSRVVGAAPEEVAAMGTLTMNLHLLLASFYRPTATKHKILMDWKAFPSDHYAIESHIAWHDLDPKESMVLIGPDEGTFEIPTEKILSYIDQHADDAALILLPGIQYYTGQLFDIQKITEYAQSRGLVVGWDLAHAYGNVHLKLHDWNVDFAAWCTYKYGNAGPGAMAGLFVHERHGRVDYREGEDSPKFRHRLTGWYGGDKSVRFKMDNNFKPIPGAGGYQISNPSAIDLASLCAALSVFDETSMAELRRKSVLMTAYLEHLLLKDTTDESRLFDIITPSEPAARGAQLSLLLRPGLLHKVAQRLQEAGIICDKREPGVVRVAPVPLYNTFTEVWTFVEQLKAALEE

Protein

Kynureninase 2: bna5-2

Gene

bna5-2

Protein

Kynureninase 2

Organism

Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)

Length

464 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.198 kDa

Sequence

MSTNGTLSKPEFPANAASKEYAASLDAADPFAGFREKFIIPSKANIASTKLAKPGLSSEPCIYFCGNSLGIQPKATQKYLEAQLDTWSSIGVCGHFTKIEDSPLKEWQNLAEQAAESMSKIVGAAPEEVAAMGTLTMNLHLLLASFFKPTATKRKILMDWKAFPSDHYAIESHLAWHHLDPKETMVLIGPDEGTYEIPTEKILSYIDQHADEAALILLPGIQYYTGQLFDIPKITEYAHSRGLIVGWDLAHAYANVPLKLHDWDVDFAAWCTYKYGNAGPGAMAGLFVHEKHGQVDYSEGEDAPKFRHRLTGWYGGDKSVRFKMDNKFKPIPGAGGYQISNPSAIDLACLCAALSVFDETSIAELRKKSVLMTAYLEYLLLKDTTDESRQFQIITPSDPAARGAQLSLLLKPGLLHKVAHRLQEAGIICDKREPGVVRVAPVPLYNTFTEIWMFVQQLKAALEG

Protein

Kynureninase 2: bna5-2

Gene

bna5-2

Protein

Kynureninase 2

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)

Length

464 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.198 kDa

Sequence

Protein

Kynureninase 2: bna5-2

Gene

bna5-2

Protein

Kynureninase 2

Organism

Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)

Length

464 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.232 kDa

Sequence

MSTNGTLSKPEFPANAASKEYAASLDAADPLAGFREKFIIPSKANIASTKLAKPGLSSEPCIYFCGNSLGIQPKATQKYLEAQLDTWSSIGVCGHFTKIEDSPLKEWQNLAEQAAESMSKIVGAAPDEVAAMGTLTMNLHLLLASFYKPTATKRKILMDWKAFPSDHYAIESHVAWHHLDPQETMVLIGPDEGTYEIPTEKILSYIDTHADEAALILLPGIQYYTGQLFDIPKITEYAHSRGLIVGWDLAHAYANVQLKLHDWDVDFAAWCTYKYGNAGPGAMAGLFVHEKHGQVDYSEGEDAPKFRHRLTGWYGGDKSVRFKMDNKFKPIPGAGGYQISNPSAIDLACLCAALSVFDETSMAELRKKSVLMTAYLEYLLLKDTTDESRQFQIVTPSDPAARGAQLSLLLKPGLLHKVAHRLQEAGIICDKREPGVVRVAPVPLYNTFTEIWMFVQQLKAALEE

Protein

Kynureninase 2: bna5-2

Gene

bna5-2

Protein

Kynureninase 2

Organism

Aspergillus niger (strain CBS 513.88 / FGSC A1513)

Length

463 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.3 kDa

Sequence

MSKSNGVSLAFPAEAATKEYAASLDSSDRLAAFREKFIVPSKANIASKKLAKPGLSPESCIYFCGNSLGIQPKATAKYLEAQLDTWSSIGVGGHFTDLEGSPLKQWQLLSEQAADSMSKIVGAKPEEVAAMGTLTTNLHLLLASFYKPTQTKHKILMDWKAFPSDHYAIESHIAWHDLDPKESMVLIGPDEGEYEISTQKIFSYIDKHADEAAMILLPGIQYYTGQLFDIQKITKYAHSRNMVVGWDLAHAFANVELKLHDWNVDFAAWCTYKYGNAGPGAMGGLFVHEQHGEVDYSAGEDAPKFRHRLTGWYGGDRSVRFKMDNKFKPIPGAGGFQISNPSAIDLACLCAALSVFDETSMADLRRKSLKLTAYLEFLLLRDYEEESRPFSIITPKDPEARGAQLSLLLKPGLLQNVAQKLQEAGIVCDKREPGVVRVAPVPLYNSFSEVWTFVKIFKDALQQ

Protein

Kynureninase 2: bna5-2

Gene

bna5-2

Protein

Kynureninase 2

Organism

Aspergillus terreus (strain NIH 2624 / FGSC A1156)

Length

463 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.31 kDa

Sequence

MSENNCSKPSFPDNAASKEYAASLDAADPLASFRDQFIIPSKANIACKRLAKPNLSPEPCIYFCGNSLGIQPKATAKYLEAQLDTWSSIGVCGHFTNLEDSPMKSWQLLAEQAAESMSKIVGADPAEVAAMGTLTANLHLLMASFYKPTATKHKILMDWKAFPSDHYAIESHIAWHNLDPKESMVLIGPDEGEYEISTDKILSYIDQHAEDAALLLLPGIQYYTGQLFDIPKITEYAKSRNLVVGWDLAHAYGNVELKLHDWNVDFAAWCTYKYGNAGPGAMAGLFVHDKHGQVDYSQGEDSPKFRHRLTGWYGGDRSVRFKMDNKFKPIPGAGGFQISNPSAIDLSCLCAALSVFDQTSVSELRRKSLKLTAYLEYLLLKDTTEDSRPFRIITPTNPEARGAQLSLLLKPGLLQGVSERLQDAGIICDKREPGVVRVAPVPLYNTYSEVWEFVQQFRAALQL

Protein

Kynureninase 2: bna5-2