besA

L-propargylglycine--L-glutamate ligase

482 amino acids

Involved in the biosynthesis of terminal alkyne-containing amino acids produced as antibiotics by S.cattleya. Catalyzes the ATP-dependent ligation of L-propargylglycine to L-glutamate to form the dipeptide L-gamma-glutamyl-L-propargylglycine. Is selective for L-propargylglycine over norvaline, allylglycine and the standard proteinogenic amino acids, except L-cysteine which can be used as a substrate to a lesser extent.

52.271 kDa

MYGAGVVTRMNEAERFHMTDPGSTKILIYAFNYADRMLEEVPYLRYSAERSLCFLGDLRDPGTRLVVITSEAVDPATLDYHLRDVFRFDEPALADVRRRLTLLTPASRAARPLDSLVLEDEALVETLRRAVAERPAGTIVDFSASPATDELGRRTGATPEEGDHAFVARWGSKSGGKEICLRAGVAVPGGTSEVLRSEAEVVEAIHRLSCGTAAARRAMVKLDAITWAASIGNVLIDRDKLRHTGDLVGSAEVIRLPAEEFRRELAEQGAIVEEFLEEITDSPSGLGHIERDGTVRVVACHDQVLSGGQYWGCRFPADERWRPEITDAVRRTGEVLSGLGHRGAFGVDFVVAGERGLLAVEINLRKVGPSHVVRYAEALVGARVGADGMLRGADGRPVYYTHGRLLEPETLGKLNPRTAVERLRAEGLLYRHDTGEGVALHVLGALNACGFVELTALARSPEAADGYSRAAQALLTGPYPSA

besA

Ferri-bacillibactin esterase BesA

289 amino acids

Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex, leading to the formation of bacillibactin monomers and to cytosolic iron release, thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB), however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB.

Belongs to the esterase D family.

32.439 kDa

MKEQTTDRTNGGTSNAFTIPGTEVRMMSSRNENRTYHIFISKPSTPPPPAGYPVIYLLDANSVFGTMTEAVRIQGRRPEKTGVIPAVIVGIGYETAEPFSSARHRDFTMPTAQSKLPERPDGREWPEHGGAEGFFRFIEEDLKPEIERDYQIDKKRQTIFGHSLGGLFVLQVLLTKPDAFQTYIAGSPSIHWNKPFILKKTDHFVSLTKKNNQPINILLAAGELEQHHKSRMNDNARELYERLAVLSEQGIRAEFCEFSGEGHISVLPVLVSRALRFALHPDGPHLSMG