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bcrR

Gene
bcrR
Protein
HTH-type transcriptional activator BcrR
Organism
Enterococcus faecalis
Length
204 amino acids
Function
Functions as both a membrane-bound sensor and transducer of bacitracin availability to activates transcription of the bcrABD operon in the presence of bacitracin (PubMed:15388429, PubMed:18227063, PubMed:30777814). Binds specifically to two inverted repeat sequences on the bcrABD promoter, irrespective of bacitracin concentration (PubMed:18227063).
Mass
22.887 kDa
Sequence
MEFNEKLQQLRTGKNLTQEQLAEQLYVSRTAISKWESGKGYPNMESLKCISKFFSVTIDELLSGEELITLAETENRSNLKKIYNYIYGILDMMAVAFIFLPLYGNSVGGYVYAVNLLSFTATTPFNLAVYWSAFAALIIIGIGKIISTHLDKEKWGGIATKCSLTITALAVCFFAAAREPYITVLVFLLLIGKIFVWIKQMGMK