BCAS2

Pre-mRNA-splicing factor SPF27

226 amino acids

Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).

Belongs to the SPF27 family.

26.27 kDa

MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPPSGQKKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

bcas2

Pre-mRNA-splicing factor SPF27

225 amino acids

Required for pre-mRNA splicing as component of the activated spliceosome. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.

Belongs to the SPF27 family.

25.863 kDa

MAGPASVAGDVFVDALPYFDQGYDATGVREAAAALVEEETRRYRPTKNYLSYLPTPDFSAFETEIMRNEFERLAARQPMELLSMKRYELPAPSSGQKNDMTAWQDCVNNSMAQLEHQAVRIENLELMAQYGTNAWKMSNDNLALMIENSQKELQNVRKEIQDLNWQRKNDQLAGGAKLRELESNWVSLVSKNYEIERAIVQLENEVAQMKQQQGDENKENIRQDF

BCAS2

Pre-mRNA-splicing factor SPF27

225 amino acids

Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961, PubMed:30705154). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).

Belongs to the SPF27 family.

26.131 kDa

MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

Bcas2

Pre-mRNA-splicing factor SPF27

225 amino acids

Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).

Belongs to the SPF27 family.

26.131 kDa

MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

bcas2

Pre-mRNA-splicing factor SPF27

223 amino acids

Required for pre-mRNA splicing as component of the activated spliceosome. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.

Belongs to the SPF27 family.

25.931 kDa

MAGTSLVAGDVVVDALPYFDQGYDAQGVREAAAALVEEETRRYRPTKNYLSYLPTPDYSAFETEIMRNEFERLSSRQPLELLSMKRYELPAPLSGQRNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLLHMIDCAQKDLQKLRKKIQDLNWQRKNSQLTAGARLREMESTWVSLVSKNYEIERAIVQMENEVYQLKERSGENKENIEDY