baiH

Gene

baiH

Protein

7-beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase

Organism

Clostridium scindens (strain JCM 10418 / VPI 12708)

Length

661 amino acids

Function

NADH-dependent flavin oxidoreductase (PubMed:8491719, PubMed:7599167, PubMed:18047844). Stereo-specific NAD(H)-dependent 3-oxo-delta4-cholenoic acid oxidoreductase involved in bile acid 7beta-dehydroxylation (PubMed:18047844).

Similarity

In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

Mass

72.029 kDa

Sequence

MDMKHSRLFSPLQIGSLTLSNRVGMAPMSMDYEAADGTVPKRLADVFVRRAEGGTGYVMIDAVTIDSKYPYMGNTTALDRDELVPQFKEFADRVKEAGSTLVPQIIHPGPESVCGYRHIAPLGPSANTNANCHVSRSISIDEIHDIIKQFGQAARRAEEAGCGAISLHCAHAYMLPGSFLSPLRNKRMDEYGGSLDNRARFVIEMIEEARRNVSPDFPIFLRISGDERMVGGNSLEDMLYLAPKFEAAGVSMLEVSGGTQYEGLEHIIPCQNKSRGVNVYEASEIKKVVGIPVYAVGKINDIRYAAEIVERGLVDGVAMGRPLLADPDLCKKAVEGQFDEITPCASCGGSCISRSEAAPECHCHINPRLGREYEFPDVPAEKSKKVLVIGAGPGGMMAAVTAAERGHDVTVWEADDKIGGQLNLAVVAPGKQEMTQWMVHLNYRAKKAGVKFEFNKEATAEDVKALAPEAVIVATGAKPLVPPIKGTQDYPVLTAHDFLRGKFVIPKGRVCVLGGGAVACETAETALENARPNSYTRGYDASIGDIDVTLVEMLPQLLTGVCAPNREPLIRKLKSKGVHINVNTKIMEVTDHEVKVQRQDGTQEWLEGFDYVLFGLGSRNYDPLSETLKEFVPEVHVIGDAVRARQASYAMWEGFEKAYSL

Protein

7-beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase: baiH