Protein
Barrier-to-autointegration factor 1
Organism
Caenorhabditis elegans
Function
DNA-binding protein which plays an essential role in nuclear envelope formation (PubMed:17170708). Required for normal chromosome segregation during mitosis (PubMed:12684533). Associates with the nuclear lamina via its interaction with LEM domain containing proteins emr-1 and lem-2 (PubMed:12684533). In association with lem-3, plays a role in radiation-induced DNA damage repair response (PubMed:22383942).
Similarity
Belongs to the BAF family.
Sequence
MSTSVKHREFVGEPMGDKEVTCIAGIGPTYGTKLTDAGFDKAYVLFGQYLLLKKDEDLFIEWLKETAGVTANHAKTAFNCLNEWADQFM