Protein
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
Function
Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (dag1) glycosylation.
Similarity
Belongs to the glycosyltransferase 31 family.
Sequence
MRSAAAALSVCVLAVLLHWICWTDRSAELLGFRAADRPKADVREVLVGVLSARHNHELRQAIRDTWLGYLKQHPHFQNRVLVKFIIGAQGCSVPLEDLEDQYSCSQLELSEAAVSGQEMAILSVPDSSALLQSDVPVLSLDFKVLHSVVITQLGVFPNKPPHYLKGNITVRLLQVDQEEAVISARFSSVSPGTAADGMFYKPVEQFILPKGFEGTLLWEAEDSTALMSVNTSALRLNNGGGVLHFRSIEEGTLPHRNALGFPGLAGGFTFTVYDVEVLSEMLRGRSGRQKIREAQLKGEDEALQEESLRHGDMVFVDVVGTYRNVPSKLLQFYKWSVENADFSLLLKTDDDCFIDVDAVLMKMQRRRLTHTSLWWGNFRQNWAVDRVGKWQELEYASPAYPAFACGSGYVVSRDLVQWLASNAQHLKAYQGEDVSMGIWMAAVGPRKYQDSGWLCEKECYVDMLSSPQHSAEELRLLWSRKNKCGDPCGCS