aviRa

Gene

aviRa

Protein

23S rRNA (guanine(2535)-N(1))-methyltransferase

Organism

Streptomyces viridochromogenes

Length

250 amino acids

Function

Specifically methylates the guanine-2535 in 23S ribosomal RNA. Confers resistance to antibiotic avilamycin, an orthosomycin antibiotic.

Mass

26.636 kDa

Sequence

MSAYRHAVERIDSSDLACGVVLHSAPGYPAFPVRLATEIFQRALARLPGDGPVTLWDPCCGSGYLLTVLGLLHRRSLRQVIASDVDPAPLELAAKNLALLSPAGLTARELERREQSERFGKPSYLEAAQAARRLRERLTAEGGALPCAIRTADVFDPRALSAVLAGSAPDVVLTDLPYGERTHWEGQVPAQPVAGLLRSLASALPAHAVIAVTDRSRKIPVAPVKALERLKIGTRSAVLVRAADVLEAGP

Protein

23S rRNA (guanine(2535)-N(1))-methyltransferase: aviRa