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aur

Gene
aur
Protein
Aurora kinase
Organism
Patiria pectinifera
Length
407 amino acids
Function
Serine/threonine protein kinase that contributes to the regulation of cell cycle progression. Involved in meiotic apparatus formation and polar body extrusion. Contributes to Plk1 activation and phosphorylation of histone H3 at 'Ser-10' during meiosis I. Required for accurate progression of early embryonic M phase. Involved in chromosome alignment and cleavage furrow formation during early embryonic cycles. May be involved in mitotic spindle formation and cytokinesis.
Similarity
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Mass
45.947 kDa
Sequence
MTPTGPSHHSMAPKRVLPAASQSNMYGNIRSASTTSTTASTSSQALRLLQNAKTSKNADNRIAHAERQGPPSAHPAAMQKPAARVAPSNENRPDPAARQHQHQQQLQQQKATGHDRVLKESQAGNSTTTTMTSTQSKEANKWSLANFDIGRPLGKGKFGNVYLAREKKSKFIVALKVLFKSQLQKAKVEHQLRREIEIQSHLRHDHILRLYGYFYDDTRVYLILEYAARGELYKEMQAQKAGHFDEDRSAVYIYQLAKALLYCHEKKVIHRDIKPENLLLDLKGDLKIADFGWSVHAPSSRRATLCGTLDYLPPEMIEGKTHDEKVDLWSLGVLCYEFLVGKPPFESQGNTETYRKITKVEFTFPKHVSEGARDLICKLLKHNPSHRLSLEGVIAHAWIQEKISQRS