Protein
Basic leucine zipper (bZIP) transcription factor atfB
Organism
Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1)
Function
Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (PubMed:21808056). Regulates the genes involved in development, stress response, and secondary metabolism through direct binding to their promoters (PubMed:23281343, PubMed:28926946). Particularly involved in the resistance to oxidative stress in asexual conidiospores (PubMed:23281343). Binds aflatoxin gene promoters carrying the cAMP-response element (CRE1) under aflatoxin-inducing conditions (PubMed:21808056, PubMed:23281343).
Similarity
Belongs to the bZIP family. ATF subfamily.
Sequence
MSVDQTLYSRARAAMADPTCAGPATFTAAGAFSQPDLMAFSLPEEEPIWGFDTIAPSMASWQGKMEQQTFCNPNMERGLKNTHVRNGQPTPPPFDDKKLQTPMGEMYPVAQYAFNSSPPEYAPPKHRSSLSEQSQTDGYGVSTRRRKASAVDQSEQQQDREKREKFLERNRLAASKCRQKKKEHTKLLETRFREVSSKKGELESEIEHLRSEVLNLKNEMLRHAQCGDEAIKIHLAQMVRLITSKDTPNRDLVSPMRSPEQMTASTPHGLSFGFDGPMQLPSEMGSPLDQRRDSEQSIMTESSYTFSTDDSFEELINV