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atfB

Gene
atfB
Protein
Basic leucine zipper (bZIP) transcription factor atfB
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
328 amino acids
Function
Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (By similarity). Regulates the genes involved in development, as well as osmotic, oxidative, and cell wall stresses (PubMed:27706915). Participates in the caspofungin paradoxical effect (CPE), where fungi grow beyond the minimum inhibitory concentration of caspofungin (PubMed:27706915). Plays a role in virulence (PubMed:27706915).
Similarity
Belongs to the bZIP family. ATF subfamily.
Mass
36.651 kDa
Sequence
MLPEQSAFGRSAMPGSDAVNPGPSPFAPPPNSFSGDFLGLSLPDEEHLWGMSPLSSSMPSWNGKNEQMFSNPNLERDLKHSHVRNGQPTPPPYGDNKTHTVGDLYSLSQCQFSNGAQNFQTHNDRRSFCEQSAINSNGGSSKRRKVRDAKMTQAEYNEQQQEKAKREKFLERNRLAASKCRQKKKEHTQLLESRYREQSDKKEQLVSEIARLRSEILGLKNEVLKHAQCGDEPIKLHLAQMVKKITYNDTTAPDLTDVPDAASSSEGPMTPRPQQALSFGFDDPLHLEPSRADGSTDHSVRRDSEASVLTENSYAFSTDESFDDLINV

Gene
atfB
Protein
Basic leucine zipper (bZIP) transcription factor atfB
Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Length
318 amino acids
Function
Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (By similarity). Regulates the genes involved in development and stress response through direct binding to their promoters (PubMed:24951443, PubMed:28830793).
Similarity
Belongs to the bZIP family. ATF subfamily.
Mass
35.914 kDa
Sequence
MSVDQTLYSRTPAAMADPTCAGPAAFTAAGAFSQPDLMAFSLREEEPIWGFDTIAPSMASWQGKMEQQTFCNPNMERGLKNTHVRNGQPTPPPFDDKKLQTPMGEMYPVAQYAFNSSPPEYAPPKHRSSLSEQSQTDGYGVSTRRRKASAIDQCEQQQEREKREKFLERNRLAASKCRQKKKEHTKLLETRFREVSNKKGELESEIEHLRSEVLNLKNEMLRHAQCGDEAIKIHLAQMVRLITSKDTPNRDLVSPMRSPEQMAASTPHGLSFGFDGPMQLPSEMGSPLDQRRDSEQSIMTESSYTFSTDDSFEELINV

Gene
atfB
Protein
Basic leucine zipper (bZIP) transcription factor atfB
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
318 amino acids
Function
Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (By similarity). Regulates the genes involved in development and stress response through direct binding to their promoters (PubMed:18448366). Particularly involved in the resistance to oxidative stress in asexual conidiospores (PubMed:18448366).
Similarity
Belongs to the bZIP family. ATF subfamily.
Mass
35.944 kDa
Sequence
MSVDQTLYSRTPTAMADPTCAGPAAFTAAGAFSQPDLMAFSLREEEPIWGFDTIAPSMASWQGKMEQQTFCNPNMERGLKNTHVRNGQPTPPPFDDKKLQTPMGEMYPVAQYAFNSSPPEYAPPKHRSSLSEQSQTDGYGVSTRRRKASAIDQCEQQQEREKREKFLERNRLAASKCRQKKKEHTKLLETRFREVSNKKGELESEIEHLRSEVLNLKNEMLRHAQCGDEAIKIHLAQMVRLITSKDTPNRDLVSPMRSPEQMAASTPHGLSFGFDGPMQLPSEMGSPLDQRRDSEQSIMTESSYTFSTDDSFEELINV

Gene
atfB
Protein
Basic leucine zipper (bZIP) transcription factor atfB
Organism
Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1)
Length
318 amino acids
Function
Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (PubMed:21808056). Regulates the genes involved in development, stress response, and secondary metabolism through direct binding to their promoters (PubMed:23281343, PubMed:28926946). Particularly involved in the resistance to oxidative stress in asexual conidiospores (PubMed:23281343). Binds aflatoxin gene promoters carrying the cAMP-response element (CRE1) under aflatoxin-inducing conditions (PubMed:21808056, PubMed:23281343).
Similarity
Belongs to the bZIP family. ATF subfamily.
Mass
35.873 kDa
Sequence
MSVDQTLYSRARAAMADPTCAGPATFTAAGAFSQPDLMAFSLPEEEPIWGFDTIAPSMASWQGKMEQQTFCNPNMERGLKNTHVRNGQPTPPPFDDKKLQTPMGEMYPVAQYAFNSSPPEYAPPKHRSSLSEQSQTDGYGVSTRRRKASAVDQSEQQQDREKREKFLERNRLAASKCRQKKKEHTKLLETRFREVSSKKGELESEIEHLRSEVLNLKNEMLRHAQCGDEAIKIHLAQMVRLITSKDTPNRDLVSPMRSPEQMTASTPHGLSFGFDGPMQLPSEMGSPLDQRRDSEQSIMTESSYTFSTDDSFEELINV