aspB

Gene

aspB

Protein

Asperlicin C monooxygenase

Organism

Petromyces alliaceus

Length

459 amino acids

Function

Catalyzes the conversion of asperlicin A to form asperlicin E, a potent cholecystokinin receptor CCK(A) antagonist.

Similarity

Belongs to the paxM FAD-dependent monooxygenase family.

Mass

50.701 kDa

Sequence

MTMHVEVGPDSTAPPHSSGIKVIIIGLGIGGLAAAIECHRKGHSVIAFDKAQELKPVGDGIALAHNAVRVIEKWGKGTVGQELGRLSSRLNTTVIYDQTGRFIAEDKLDGFKAGEGHLLPRGELSQVMYKHAKSLGIDMRLASEVDEYWEDENSAGVIVDGEKITADCVVACDGVNSKARRHIIGYEPELRSSGSCVFRGWMTTEEPLVGSHWLLSHTDQADQVKVFAGDGVHVLLSTIQHGKMVFWLCTHKDNDCYDRKKEAPPTPEVDGMIHLIRDWPMRGQIESTIRKTLAKNVMHYPLLIREALSNWRSKGGRMVIIGDAAHPFLPVSGQGAAQAIEDAAVLAITLHLAGKEEVPLALHALEKIRLPRTALLQRSSLELERFWLNIDWPEVEKCPELLTIPRPKWIHGHDCQTHAYTEFAKVVSAIQMREEYHPLGGPRDSTNGESLLALLRQDT

Protein

Asperlicin C monooxygenase: aspB

Gene

aspB

Protein

Aspartate aminotransferase

Organism

Bacillus subtilis (strain 168)

Length

393 amino acids

Similarity

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Mass

43.088 kDa

Sequence

MKLAKRVSALTPSTTLAITAKAKELKAAGHDVIGLGAGEPDFNTPQHIIDAAVRSMNEGHTKYTPSGGLAELKNSIAEKFKRDQNIEYKPSQIIVCTGAKHALYTLFQVILDEEDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEENHFKISPEQLKNAITEKTKAIVINSPSNPTGVMYTEEELSALGEVCLEHDILIVSDEIYEKLTYGGKKHVSIAQLSDRLKEQTVIINGVSKSHSMTGWRIGYAAGSEDIIKAMTNLASHSTSNPTSIAQYGAIAAYNGPSEPLEEMREAFEHRLNTIYAKLIEIPGFSCVKPEGAFYLFPNAKEAAQSCGFKDVDEFVKALLEEEKVAIVPGSGFGSPENVRLSYATSLDLLEEAIERIKRFVEKHS

Protein

Aspartate aminotransferase: aspB

Gene

aspB

Protein

Asparagine--oxo-acid transaminase

Organism

Streptococcus mutans serotype c (strain ATCC 700610 / UA159)

Length

393 amino acids

Function

Catalyzes the transamination reaction between L-asparagine and 2-oxoglutarate to produce L-glutamate and 2-oxosuccinamate (PubMed:22569339). Is not active with pyruvate as amine acceptor (PubMed:22569339). May also use other amino acids as substrates.

Similarity

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Mass

43.501 kDa

Sequence

MTKLSRRVLEMEESVTLATSARAKTLKAQGRDVLELSLGQPDFVTPKNIQEAAMKSIRDGRASFYTIASGLPELKDAISQYFEKFYGYSVERKQIVVGTGAKFILYALFAAVINPKDEVIIPTPFWVSYADQIKMNDGVPVFIRTSEENHFKATVEQLEAARTNKTKMIVLNSPSNPTGMIYSKKELEAIGNWAVKHDILILSDDIYGRLVYNGARFTPISTISQPICQQTIVINGVSKTYSMTGWRVGYAVGDPEIIGAMSKIVSQTTSNLTTAAQYAAIEALIGNQDTVEVMRQAFEERLNTIYPLLAKVPGFHVVKPEGAFYFFPNVKKAMEMKGYTDVTEFTTALLEETGVALVTGAGFGAPENVRLSYATDMVTLKEAINRIQAFMEK

Protein

Asparagine--oxo-acid transaminase: aspB