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arpc1a-b

Gene
arpc1a-b
Protein
Actin-related protein 2/3 complex subunit 1A-B
Organism
Xenopus laevis
Length
370 amino acids
Function
Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).
Similarity
Belongs to the WD repeat ARPC1 family.
Mass
41.622 kDa
Sequence
MSLHQFLLEPITCHAWNKDLTQIAISPNNHEVHIYKNSGNQWVKCHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKTRVFSAYIKEVDEKPASTPWGSKMPFGQMMAEFGGVSSGGWVHSVSFSASGNKLAWVSHDSTVSVADASKNMSVSQLKTEFLPLLSVIFVSENSLIAAGHDCCPMLFTYDEQGSLTFVSKLDIPKQSTQRNISAMERFRNMDKRATTEDRNTTLETLHQNSITQVSIYDGDKTDCRKFCTTGIDGAMTIWDFKTLESYIQGLRIM