Function
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex (By similarity).
Sequence
MESKVIVIHHGSHSLKIGLASESVPKTIPNYIARKKKEKISTPTITTTETPTIVSPVESTIINNKSNENNDDIMKIDVENTVTPSEAVGTTTEDVKSTLPMATTITTDEQVKPTSSTSSTSTTEEVEIKPTESMDIDKPITDSKTNITSNIKIEQPPPPINIQTQTKIHIPKKLLEEVEQSVKETTKLLPPVDYIKVRQKPTLYNENNSTTFEIIKKKKKKTSSLSSLTNVSTTPPPYVPQPLNYNEIDYCIGDDAIAVSRDKDKWFAYQPITMSTFNTGIYHSVQSMFDDITQMWKYAIQRYLNIPSSDLSSYGCVYVVTDNIDRKSLKQITTLLLKELQFTSVLFFQESICSSFGVSMATQSCVIDLGHQKISIACVDEGYLLPNTRLTLGYGGEQLTKLLEYLLTGMDKSDSDTLTRQMVAKQIHKYYFPFKSSIYELVDFSPFYLNVFDNIKIENLDYYYNDFQKQRVGTFKVKDIKHDKHMNIYHFNADEVYQVVGMSLFYPNILSQFGGSSVNYLIKSRSLANTSESNLYVEDQKHYYNHYLSSYDHEDPFDDHSHILSFAQNNTSRDNKDGSNNNNIINNNIINNIINNNNNNNNNSSSSSNNNNNNNNSGSNSNINSYNNNNNNNNNNNNNNNNNNNNSFNNVTIVTSTLNSNSTVPSTLNSNSTVPSISNSNSTVPSTSTSTTSSPTKKLKIESSSNCEDNYIDIPLDIAILKSVSQLERSDINKKKYLSNILLVGGGALAPGIQDVLRVCIFKQLEQQYQAQQLQFQQQLQQQQQQQQQLQQQLQNSTNSATTTPTPSSTTIMPLENYIGFANSSIRSDVDCRHAGWRGGAILGCLESTREIWITRSEWQDGKNSSALNKLPF