Protein
Actin-like protein ARP10
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Function
Pointed-end-associated component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity). The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint. May regulate the association of the dynactin complex with the plasma membrane.
Similarity
Belongs to the actin family. ARP10 subfamily.
Sequence
MSNTIVIVYLGANRIEIGRSADACPQEIIAWKTGSINEKNREELKKIFEHYFQICNILGNREVQVLILEDIFISVVEKRIICSILFKEFDCAHVSFVPRAIVHCLSCNTRNAIVIDIGTNYTTCVPIFDLRPLQQFIKYSKRGKRQVESRIPLPGSLYMPIFFDEEYNSKNCEVDETPVINLVKNIVESLPIDLRRPLRENIIIVNIEEAYETVIRNLFKLKMDTSKIQFPKNYWQAGSACAKILLHYKGSNIVGIERDEFYNNPHIAPDWFDYYFRTGVKRLQ