arnt2

Aryl hydrocarbon receptor nuclear translocator 2

737 amino acids

Transcription factor that plays a role in the development of the hypothalamo-pituitary axis. Specifically recognizes the xenobiotic response element (XRE) (By similarity). Isoform 1 acts as a transcriptional activator (PubMed:11072074). Isoform 3 acts as a transcriptional repressor (PubMed:10960127, PubMed:11072074).

80.972 kDa

MATPAAVNPSEMGTDLPGPVSMPGAVVGAGQVRMTGAMPGRGGKRRSAGMDFDDEDGEGPSKFSRYDDDQIPGDKERYARENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNTSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNHPQSEWFGSTLFEQVHPDDVDKLREQLSTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSAPLDHISLNRLSSMRKRYRNGLGPSKEGEAQYSVVHCTGYIKAWPPAGMTIPDEDTEAGQTSKYCLVAIGRLQVTSSPVSMDMNGLSVPTEFLSRHNSDGIITFVDPRCINVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRMKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQQAELEVHQRDGLTAYDLSQVPVSGVSAGVHESGKTIDKTESLFSQERDPRFSDIYTGISTSEKKMMVPSSTSGGQQLYSQGSPFQPGHSGKSFSSSVIHVPGVNDIQSTAGSAGQNLSQISRQINTGQVSWSGNRPPFSGQQIPAQSNKAQSSPFGIGSSHSYQADPSSYSPLSSPATSSPSGNAYSNLANRNTAFDVSGESSQSGGQFQGRPSEVWSQWQSQHHSQQAGDPHPHTQASQTEVFQDMLPMPGDPTQGTTNYNIEDFADLGMFPPFSE

ARNT2

Aryl hydrocarbon receptor nuclear translocator 2

717 amino acids

Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function (PubMed:24022475). Specifically recognizes the xenobiotic response element (XRE).

78.691 kDa

MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASAAGTQQIYSQGSPFPSGHSGKAFSSSVVHVPGVNDIQSSSSTGQNMSQISRQLNQSQVAWTGSRPPFPGQQIPSQSSKTQSSPFGIGTSHTYPADPSSYSPLSSPATSSPSGNAYSSLANRTPGFAESGQSSGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE

Arnt2

Aryl hydrocarbon receptor nuclear translocator 2

712 amino acids

Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. Specifically recognizes the xenobiotic response element (XRE).

77.902 kDa

MATPAAVNPPEMASDIPGSVALPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMSGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWLLIRTSSFTFQNPYSDEIEYVICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASASGSQQIYSQGSPFPAGHSGKAFSSSVVHVPGVNDIQSSSSTGQNISQISRQLNQGQVAWTGSRPPFPGQPSKTQSSAFGIGSSHPYPADPSSYSPLSSPAASSPSGNAYPSLANRTPGFAESGQSGGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE

Arnt2

Aryl hydrocarbon receptor nuclear translocator 2

712 amino acids

Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. Specifically recognizes the xenobiotic response element (XRE).

77.958 kDa

MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMSIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMSGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWLLIRTSSFTFQNPYSDEIEYVICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPTGVHEAGKPVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASASGSQQIYSQGSPFPAGHSGKAFSSSVVHVPGVNDIQSSSSTGQNISQISRQLNQGQVAWTGSRPPFPGQPSKTQSSAFGIGSSHPYPADPSSYSPLSSPAASSPSGNAYPSLANRTPGFAESGQSGGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE

arnT2

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2

583 amino acids

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

Belongs to the glycosyltransferase 83 family.

65.17 kDa

MTSRIQMHRTSPPPAYGTSAPPSGFTLGASTTSTLQRWALPLLLVAFGLFYLLPLTSHGLWIPDETRYAQISQEMLLSGDWVAPHFMGIRYFEKPIAGYWLIAIGQAVFGDNLFGVRIASALSTGLSVLLAYLITRRMWNDPRKSFAAALLYMSFGLIAGQAGYSNLDPQFTLWVNLSLVALWFALDGRSTRERLLAWAGLGVACGMGFMTKGFLAWLLPVLIALPYMIWQRRLGELVRYGLVAVLVAIGISLPWVLSIHAHEPDFWRFFFWHEHIRRFAADNAQHTRPWWFYLPLLVASSLPWAALLPGTFMQAWKDKRQAPTGFLLLWFLLPLAFFSLSRGKLPTYIMPCLLPLAVLMGSALIDRINAIQGRSIRINSLLNLLIGVAAMVALLYIQLTRPVYGHNEMLGLSLVFIMLMGWIIANLLPAARPLQYWPAPALGIWLLVALLPAGMPGFIVHNQMPDQFIKEHIEELRQTKTLLSNDLGAASALAWRLQRPEVTLYNTEGELKYGLAYADSAQRKVSMAEVGQWVSEARKQGSVGVVMRVKDVVESEEVALLPPGGKRYEEGNMLVLILPQSQP

arnT2

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2

553 amino acids

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

Belongs to the glycosyltransferase 83 family.

63.064 kDa

MLNNRASKIGAILLALFFVLTYLFPLNSRLLWQPDETRYAEISREMVVSGNWIVPHMLDIRYFEKPIAGYWINNISQLIFGHTNFAVRFGSVISILLSALLIYLLARMMWRNRQVAFVASLIYLSMFLVFSVGTYSVLDPMLALWVTASMVCCFWALKATTAKTRILAWITLGLACGMAFMTKGFLALAIPVIVMIPVTLYQKQFTRMLLYGVLAVLSAALISLPWVLAVAKAEPDYWHYFFWVEHIQRFSGDDAQHSSPFWYYIPIILLGVIPWLGLLPGALTSAWKKRRKRPELFFLLCWFVVPFLFFSIAKGKLPTYMLPFMGPLAMLMAKYGVDCARKFKMKALRINGYINIFIGVAAVVAILIIQLVSSKPIYMPYEWSKWVLAIVAFSLWGIIGYLCSTLNGKHWLWAASCSLGVSLCIGQAIPNSSIDGKLPQEFIRQNIDTLNASKYIVSNSVGVGAGLAWELQRSDIYLYERTGELTYGIEYPDSQHRLLKPESFEQWLENARKEGNVSVVITYKDPKKLAQMPRPEELVTNRRMAILTYEKRK

arnT2

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2

550 amino acids

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

Belongs to the glycosyltransferase 83 family.

61.716 kDa

MKSLKPGIGLMCIIALYYLLPLSFRSLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPSVGYWINNLSQWAFGHTNFAVHFGSAFSIALTALMVYWLALRLWQDRWLGLTAAAIYSSCLLVYSIGTYAVLDPMIALWLAAAMCAFWQAVQAPRGWRKGLGYLALGIACGLGFMTKGFLALAVPVLSVLPWVIAQKRWKEVFIYGPLALLGAVATSLPWVIAIARREPDFWHYFIWVEHVQRFAEDNAQHKAPFWYYLPVLLAGTLPWLGLLPGALRRAWRERQTQSGAFYLLGWVVMPLLFFSLSKGKLPTYILPSFAPLALLMARYAATCGGRALKVNGVLNLLFGLLCVITVASVLAPWGLAQHPLFVQNEVRKVLLGVLGFLVWAAVGGLTLRAPTVCWRWAALCPLGIALLVGQAIPQQVIDAKQPQSFIQTVRPQLEKSRFIFANSVGVAAGLAWELQRSDISLFELQGELAYGLSYPDAADRFIREEDFSDWLRERCKEGSVALVVLLPDGETQISHLPRADETYRRGRLVLLAYHQRRP

arnT2

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2

549 amino acids

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

Belongs to the glycosyltransferase 83 family.

61.799 kDa

MSKRWALPLLLGIFLLAYLLPLGSHGLWIPDETRYAQISQEMLLSGNWVSPHFMNLRYFEKPAAGYWMIAIGQAVFGQNLFGVRFASALSTGLSVLLCFLIARRLWNEPRKSFVCALLYMSFVIVAGQAGYANLDPQFTFWVNLSLVALWFALDSRANGQRLAGWAVLGLACGMGFMTKGFLAWLLPVLIALPWMLWQKRWKELLLYGPVAIAVAIIVSLPWALAVHGQEPDYWRFFFWHEHIRRFAGDDAQHDAPWWFYLPLLVAFSLPWVGMLPVAFKQAWQTRRETGIAFLGLWLLMPLLFFSLSNGKLPTYILPCLLPLALLLGHALADRLRLEQGRALGLNGLLNLLLGLVTLIGLVYVQLKRPLYDHELHSLVLVFIALTGWIISNLLQAFRPLQCWAAPAVGSLLLIALLPAALPRSVVANKMPDQFVLAHQKELTATTHLLSNDLGAASALSWRVKRPQVALYNTIGELKYGLAYPDGIQQRVDPDQVQQWMREARKTGSVGVVMRVKGQDELDELDRLPKDGVRYEQGNLVIMILPQEAS