Protein
Arginine/ornithine antiporter ArcD1
Organism
Lactococcus lactis subsp. cremoris (strain MG1363)
Function
Catalyzes electroneutral exchange between L-arginine and L-ornithine. Can also efficiently translocate L-histidine and L-lysine. ArcD1 is the main L-arginine/L-ornithine exchanger in the arginine deiminase (ADI) pathway.
Similarity
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
Sequence
MDAENKKGIGLAALVAIIVSGAIGGGVFNLSNDLATNASPGGVVISWIVIGFGILMLVLSLNHLVVNKPELSGVSDYARAGFGNMVGFISGWGYWLSAWAGNIAFAVLMMTSVDYFFPGVFQAKNGSLTILSVIVVSIVSWGLTLLVMRGVEGAAAINAIVLVAKLIPLFVFVIAGIVTFKAGVFSAHFWQNFVANTNADGVIKSLTWSNMTGGDLFSQVKGSLMVMIWVFVGIEGAAMMGDRAKRKSDAGKASIFGLIALLVIYILLSLLPFGFMSQQELANTGQPGLVHILNAMVGGWGGSLMAIGLVISLLGAWLSWTMLPVEATQQLSEQKLLPSWFGKLNDKGAPKNSLLLTQLIVQIFLIVTYFVADAYNVFVYLCTAVIMICYALVGLYLFKLGIQEKKTSNIIIGFIAAAFQILALYYSGWQFVWLSLILYAVGFILYALGKKEYGTKMSTTEVIATFILTVLGILAVFGVYGNWLGLQDALGIDGNTLLVAVVPLIVVTFIVYFVVRSDINKKGIKN