Protein
Modification methylase AplI
Organism
Arthrospira platensis (strain NIES-39 / IAM M-135)
Function
This methylase recognizes the double-stranded sequence 5'-CTGCAG-3', causes specific methylation on C-4 on both strands, and protects the DNA from cleavage by the AplI endonuclease.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Sequence
MSNRLSYWEYLHQELKLNADIQSQLVVLDLFAGCGGFSLGFKAAGFQTIGYEMLADAAATYTRNLQDPCYCQTLEIGQDLCNHPDVIIGGPPCQPFSVGGLQKGPRDSRDGLPIFIDAIARYQPEIAIFENVRGMLYKNRQYLEKIVAELERLNYRVDIKLINAVNYGVPQKRERLFVVAYQTAWNWPEAETLAIPYTAGDAIYDTASTIPIGAKFLTPSMLEYIGRYEAKSKCVKPRDIYLDIPCRTLTCRNLSGATSDMLRLLLPDGRRRRLTVREAARLQSFPDWFELVGSENSQFNQIGNAVPPLLAKAIAKSVKMTLENKPSRPTDYFSPFPQQLKLPFA