Protein
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).
Similarity
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Sequence
MANGLFTYVAISLFTIGPLLALFIPFVWRLVGSSLGWYLRRKTDGRRCHILEVVEADERKYRDSKSAKGRKAEKEDRDTFNNTEATGTSDGKVYDKDWDGIVGFFHPFCNAGGGGERVLWAAIRATQKRWPKAKCVVYTGDHDVSKEAILSRVEQRFNIHLHPPTVNFLYLSTRRWVLASTWPYFTLAGQSFGSLIMAWDAFSLLVPDIFVDTMGYAFALGFSRFLFRDVPTAAYVHYPTISTDMLESLDPASAVGSQGVNAGKGTGAKGRAKKIYWQLFARLYSLMGASVDVVMTNSTWTQAHIEKLWGPVRNLTGAVPGIKSKVNPIAVVYPPVAVEELEQEVEVSPESEKRRENVLLYIAQFRPEKNHQLIVQAFAEFLKSGSEAARDAKLVLVGSVRDDYDSKRVYKLRLLVNELHIKDRVEFHLDASWPDILEWLRRASVGVNGMWNEHFGIGVVEYQAAGLISVVHDSGGPKLDIVVEVDGEPTGFHATTSKEFAEGFEKALSLPNPYAVRLRARKSAKRFTEEEFARRWIEQLEKCVAIKAVEKPKSRQ