aglA

Alpha-glucosidase

985 amino acids

Hydrolyzes malto-oligosaccharides, but has a low activity toward soluble starch.

Belongs to the glycosyl hydrolase 31 family.

108.913 kDa

MVKLTHLLARAWLVPLAYGASQSLLSTTAPSQPQFTIPASADVGAQLIANIDDPQAADAQSVCPGYKASKVQHNSRGFTASLQLAGRPCNVYGTDVESLTLSVEYQDSDRLNIQILPTHVDSTNASWYFLSENLVPRPKASLNASVSQSDLFVSWSNEPSFNFKVIRKATGDALFSTEGTVLVYENQFIEFVTALPEEYNLYGLGEHITQFRLQRNANLTIYPSDDGTPIDQNLYGQHPFYLDTRYYKGDRQNGSYIPVKSSEADASQDYISLSHGVFLRNSHGLEILLRSQKLIWRTLGGGIDLTFYSGPAPADVTRQYLTSTVGLPAMQQYNTLGFHQCRWGYNNWSDLADVVANFEKFEIPLEYIWTDIDYMHGYRNFDNDQHRFSYSEGDEFLSKLHESGRYYVPIVDAALYIPNPENASDAYATYDRGAADDVFLKNPDGSLYIGAVWPGYTVFPDWHHPKAVDFWANELVIWSKKVAFDGVWYDMSEVSSFCVGSCGTGNLTLNPAHPSFLLPGEPGDIIYDYPEAFNITNATEAASASAGASSQAAATATTTSTSVSYLRTTPTPGVRNVEHPPYVINHDQEGHDLSVHAVSPNATHVDGVEEYDVHGLYGHQGLNATYQGLLEVWSHKRRPFIIGRSTFAGSGKWAGHWGGDNYSKWWSMYYSISQALSFSLFGIPMFGADTCGFNGNSDEELCNRWMQLSAFFPFYRNHNELSTIPQEPYRWASVIEATKSAMRIRYAILPYFYTLFDLAHTTGSTVMRALSWEFPNDPTLAAVETQFMVGPAIMVVPVLEPLVNTVKGVFPGVGHGEVWYDWYTQAAVDAKPGVNTTISAPLGHIPVYVRGGNILPMQEPALTTREARQTPWALLAALGSNGTASGQLYLDDGESIYPNATLHVDFTASRSSLRSSAQGRWKERNPLANVTVLGVNKEPSAVTLNGQAVFPGSVTYNSTSQVLFVGGLQNLTKGGAWAENWVLEW

aglA

Probable alpha-glucosidase

551 amino acids

Belongs to the glycosyl hydrolase 13 family.

62.576 kDa

MTMNETTSSLLEPDRDWWRGAVIYQIYPRSFQDTNGDGIGDLQGITARLPHIAGLGADAIWISPFFTSPMRDFGYDVSNYVDVDPIFGTLEDFDALIAEAHRLGLRVMIDLVLSHTSDRHPWFVESRSSRSNAKADWYVWADSKPDGTPPNNWLSIFGGSAWQWDPTRLQYYLHNFLTSQPDLNLHNPQVQEALLAVERFWLERGVDGFRLDTINFYFHDRELRDNPALVPERRNASTAPAVNPYNYQEHIYDKNRPENLEFLKRFRAVMDEFPAIAAVGEVGDSQRGLEIAGEYTSGGDKVHMCYAFEFLAPDRLTPQRVAEVLRDFHRAAPEGWACWAFSNHDVVRHVSRWADGVTDHDAHAKLLASLLMSLRGTVCIYQGEELALAEAELDYEDLQDPYGIQFWPDFKGRDGCRTPMVWESLPDGGFSSATPWLPISQSHIPRAVAVQEGDPASVLHHYRRFLAFRKANPALAKGEIEFVETRGSLLGFLRSHGNEKVFCLFNMSDEAATKELPMKRLEPLEGHGFVSEILDHEVKLPAWGAFFARLA

aglA

Alpha-galactosidase A

545 amino acids

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

Belongs to the glycosyl hydrolase 27 family.

60.148 kDa

MIQGLESIMNQGTKRILLAATLAATPWQVYGSIEQPSLLPTPPMGFNNWARFMCDLNETLFTETADTMAANGLRDAGYNRINLDDCWMAYQRSDNGSLQWNTTKFPHGLPWLAKYVKAKGFHFGIYEDSGNMTCGGYPGSYNHEEQDANTFASWGIDYLKLDGCNVYATQGRTLEEEYKQRYGHWHQVLSKMQHPLIFSESAPAYFAGTDNNTDWYTVMDWVPIYGELARHSTDILVYSGAGSAWDSIMNNYNYNTLLARYQRPGYFNDPDFLIPDHPGLTADEKRSHFALWASFSAPLIISAYIPALSKDEIAFLTNEALIAVNQDPLAQQATLASRDDTLDILTRSLANGDRLLTVLNKGNTTVTRDIPVQWLGLTETDCTYTAEDLWDGKTQKISDHIKIELASHATAVFRLSLPQGCSSVVPTGLVFNTASGNCLTAASNSSVAFQSCNGETSQIWQVTPSGVIRPVSQTTQCLAADGNLVKLQACDSTDSDGQKWTYPVTGNLKNAKTDGCLTEGSVQMKSCLYERDGQVFGLPSGVQLA

aglA

PTS system alpha-glucoside-specific EIICB component

540 amino acids

Involved in the transport and simultaneous phosphorylation at O-6 of the glucosyl moiety of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses. Can also transport maltose, isomaltose and maltitol, phosphorylating at O-6 of their non-reducing glucose portion.

58.373 kDa

MLSQIQRFGGAMFTPVLLFPFAGIVVGIAIMLRNPMFVGEALTAPDSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVLVSFLTWNYFINAMGMTWGHFFGVDFSAEPTAGSGLTMIAGIKTLDTSIIGAIVISGLVTALHNRYFDKPLPVFLGIFQGSSFVVIVAFLAMIPCAWLTLLGWPKVQLGIESLQAFLRSAGALGVWVYIFLERILIPTGLHHFVYGPFIFGPAVVEGGLQVYWAEHLQAFSQSTEPLKTLFPEGGFALHGNSKVFGSVGIALALYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFISPLLFAVHAVLAATMATVMYICGVVGNFGGGLLDQFLPQNWIPMFHHHASMMFIQIGIGLCFTALYFVVFRTLILRLNLKTPGREESEIKLYSKADYQAARGKTTAAAAPETRLGQAAGFLQALGGADNIESINNCATRLRIALVDMAKTQSDDVFKALGAHGVVRRGNGIQVIVGLHVPQVRDQLENLMKDSLSTEHTTMTEAVS

aglA

Probable alpha-galactosidase A

537 amino acids

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

Belongs to the glycosyl hydrolase 27 family.

59.213 kDa

MNQGTKSILLAATLAAIPWQVYGSIEQSSLLPIPPMGFNNWARFMCDLNETLFTETADAMAANGLRDAGYNRINLDDCWMAYQRSDNGSLQWNTTKFPHGLPWLAQYVKAKGFHFGIYEDSGNMTCGGYPGSYNHEEQDANTFALWGIDYLKLDGCNVYATQGRTLEEEYKQRYGHWHQVLSKMQHPLIFSESAPAYFAGTDNNTDWYTVMDWVPIYGELARHSTDILVYSGAGSAWDSIMNNYNYNTLLARYQRPGYFNDPDFLIPDHPGLTADEKRSHFALWASFSAPLIISAYIPALSKDEIAFLTNEALIAVNQDPLAQQATFASRDNTLDILTRNLANGDRLLTVLNKGNTTVTRDIPVQWLGLTETDCTYTAEDLWDGKTQKISDHIKIELASHATAVFRLGLPQGCSSVVPTGLVFNTASGNCLTAASNSSVAFQSCNGETSQIWQVTLSGVIRPVSQTTQCLAADGNSVKLQACDSTDSDGQNWTYAVTGNLKNAKTDGCLTEGSVQMKSCLYERDGQVFGLPSGVQLS

aglA

Probable alpha-galactosidase A

534 amino acids

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

Belongs to the glycosyl hydrolase 27 family.

58.727 kDa

MRLITRWIPLANALASTMPVQVVASIENPSLLPTPPMGFNNWARFMCDLNETLFVETTDAMASNGLLEAGYNRINLDDCWMNYDRAENGSLEWNVTKFPRGLPWLGQYVKSKGFNFGIYEDSGNLTCGGYPGSEGYEEIDAETFAAWGIDYLKLDGCNVYPKEGRTLQEEYKYLYGNWHEILSKMQQPLIFSESAPAYFSMTDNLTDWHTVMDWVPEYGELARHSVDILVYSGEGSAWDSIMTNYKFNTLVARYQRPGYYNDPDFLIADHPGLSLDEKRSQFALWASFSAPLIISAHIPDLSSEDLEYLTNQALIAVDQDPLAQQATLASRDGSLDVLTRNLADGSRLVTILNHGSESIETDISLDILGLSTDCTYKAQDLWGGSTQTIKDAIRIKLNTHATAVYKIDTDEKCSQVIPTGLIFNTASGKCLTGTSSSVGSESCNGSKSQIWQIDASGVIRTLSEQSKCLTADGKAISLQECSENNGQKWSYAITGNLKNADTGYCLTNGGGVSACGFETNSQVFGLPAGVHVAL

aglA

Probable alpha-galactosidase A

534 amino acids

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

Belongs to the glycosyl hydrolase 27 family.

58.739 kDa

MRLITRWIPLANALASTMPVQVVASIENPSLLPTPPMGFNNWARFMCDLNETLFVETTDAMASNGLLEAGYNRINLDDCWMNYDRAENGSLEWNVTKFPRGLPWLGQYVKSKGFNFGIYEDSGNLTCGGYPGSEGYEEIDAEIFAAWGIDYLKLDGCNVYPKEGRTLQEEYKYLYGNWHEILSKMQQPLIFSESAPAYFSMTDNLTDWHTVMDWVPEYGELARHSVDILVYSGEGSAWDSIMTNYKFNTLVARYQRPGYYNDPDFLIADHPGLSLDEKRSQFALWASFSAPLIISAHIPDLSSEDLEYLTNQALIAVDQDPLAQQATLASRDGSLDVLTRNLADGSRLVTILNHGSESIETDISLDILGLSTDCTYKAQDLWGGSTQTIKDAIRIKLNTHATAVYKIDTDEKCSQVIPTGLIFNTASGKCLTGTSSSVGSESCNGSKSQIWQIDASGVIRTLSEQSKCLTADGKAISLQECSENNGQKWSYAITGNLKNADTGYCLTNGGGVSACGFETNSQVFGLPAGVHVAL

aglA

Probable alpha-galactosidase A

532 amino acids

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

Belongs to the glycosyl hydrolase 27 family.

58.991 kDa

MDTTKSLLSTLIAIMIPLSLGSVSSPNLLPTPPMGFNNWARFMCDLNETLFLETASAMISTGLLEAGYNRVNLDDCWMAYDRAADSSLQWNTTKFPHGIPWLARHLKAQGFHVGIYEDAGNLTCGGYPGSFGHEALDAQTFAAWGIDYLKLDGCNVFPEHSRTLEEEYKARYAHWHSILKQMHHPLIFSESAPAYFADPANLTSWYEVMDWVPAFGELARHSTDILVYVGEGSAWDSIMVNYRYNTLLARYQRPGYINDPDFLIPDHPGLTLEEKRSQFALWASFSAPLIVSAYIPGLSSEELAILRNEELIRVDQDVLGLQATLASRGLEVDVLTRSLEGGDRLLTVLNRGDGVAVVSVPVEWMGLQRGCPYVVKNLWDGEVQVLEEEIVIRLNSHATQVYRIALPDECSTVIPTGIVFNTASGNCLTDENGERVGFEACRGSETQIWQVSELGYLRPLSRTSHCLTGGSQASVQLCTEQKNQQWAYAITGILKNEHTEMCLTEGTGISQCGFERDSQVFGLPSGVDIKPS

aglA

Probable alpha-galactosidase A

532 amino acids

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

Belongs to the glycosyl hydrolase 27 family.

59.159 kDa

MYTTKSLLSTLIPIMIPLSLGSVSSPNLLPTPPMGFNNWARFMCDLNETLFLETASAMISTGLLEAGYNRLNLDDCWMAYDRAADSSLQWNTTKFPHGIPWLAYRLKTQGFHLGIYQDAGNLTCGGYPGSFGYEALDAQTFAAWGIDYLKLDGCNVFPEHSRTLEEEYKARYAHWHNVLRQMHPPLIFSESAPAYFADPANLTSWYEVMDWVPAFGELARHSTDILVYVGEGSAWDSIMVNYHYNTLLARYQRPGYFNDPDFLIPDHPGLTLEEKRSQFALWASFSAPLIVSAYIPGLSGEELAILRNEELITVDQDVLGLQATLASRGEEVDVLTRSLAHGDQLLTVLNRGDGVPVVRVPVEWMGLQRGCAYVVKNLWDGEVQVLEEEIVIRLNSHATQVYRIALPEECSTVIPTGIVFNTASGNCLTDENGERVGFEACRGSETQVWQVSELGHLHPLSRTSHCLTAGSQASVQLCTGQKNQQWTYEITGNLKNEHTKMCLTEGTGISQCGFERDSQVFGLPSGVDIKSS

aglA

Probable alpha-galactosidase A

529 amino acids

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

Belongs to the glycosyl hydrolase 27 family.

58.367 kDa

MKALFAAITMAHALLQTQASLQNPNLLPTPPMGFNNWARFMCDLNETLFVETADAMAANGLLAAGYNWLNLDDCWMTHQRAPNNSLMWNTTKFPRGLPWLGSYVKAKGFRFGIYEDAGNLTCGGYPGSLGHEELDARTFADWGVEYLKLDGCNVFPEGGRTSEQQYEHLYGLWHRILSGMPHPLVFSESAPAYFANEKNLSDWYTVMDWVPRYGELARHSTDILVYAGEGSAWDSIMVNYRYNTLVARYQRPGYYNDPDFLIPDHPGLTMDEKKSHFGLWASFAAPLIISAYIPGLSEEDIGYLTNRDLIAVDQDPLAQQATLASRDDEVDVLTRSLADGSRLVSVLNRGNSSVQRVIPLQWLGLNPGQRYQARNLWDGTEKRIRKDLTVTVRSHATEIYKFTGSNGRVDAVSTGIVFNTASGNCLTGDAAGVGFAPCTGGEKQIWQVRGSELRPLSLLGECLTADGTRLSLRPCAGDEAQMWSYHISGNLKSGHEGGCLTEGHGVASCGWELNSQVFGLPSGVRVSGY

aglA

Probable alpha-galactosidase A

525 amino acids

Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.

Belongs to the glycosyl hydrolase 27 family.

57.347 kDa

MHPSMTLLAILPPLVRASIGNPHLLPTPPMGFNNWARFMCNLNESLFLDTAAAMLDTGLHAAGYTRLNLDDCWMASHRAPNGSLPWDPTKFPHSLPWLSAQLRSLGFSLGIYQDAGNVTCGGYPGSYGFEELDAHTFAEWGVDYLKLDGCNVSPAGAVSLADEYRARYARWHSVLGAMPHPLVFSESAPAYFVDPQNATAWYGVMDWVPAYGELARHSTDILVYEGEGSAWQSIMVNYRYNTLLARYQRPGYFNDPDFLIADHPGLSLVEKRSHFALWASFGAPLIISADVPGLSKEVIAVLTNADLIRVDQDALGLQATLASRSEHLDVLTRSLDGGDRLVTILNRGDGGLAVKVPVGWMGLQRCAYQAKNLWDGEIQEIEEDIEVQLDSHATEVFRVSLPPDCPMVIPTGIVFNTASGNCLTDGEALAFEPCRGQDLQVWQVEESGILRPLSRTSHCLTAIGDNVVVKPCTGRPGQRWTYHITGNLQNQHTGACLTEGTGIDVCGFELDSQVFGLPSGVDIEA

aglA

Alpha-glucosidase

480 amino acids

Alpha-glycosidase with a very broad specificity. Hydrolyzes maltose and other small maltooligosaccharides but is inactive against the polymeric substrate starch. AglA is not specific with respect to the configuration at the C-4 position of its substrates because glycosidic derivatives of D-galactose are also hydrolyzed. Does not cleave beta-glycosidic bonds.

Belongs to the glycosyl hydrolase 4 family.

55.047 kDa

MPSVKIGIIGAGSAVFSLRLVSDLCKTPGLSGSTVTLMDIDEERLDAILTIAKKYVEEVGADLKFEKTMNLDDVIIDADFVINTAMVGGHTYLEKVRQIGEKYGYYRGIDAQEFNMVSDYYTFSNYNQLKYFVDIARKIEKLSPKAWYLQAANPIFEGTTLVTRTVPIKAVGFCHGHYGVMEIVEKLGLEEEKVDWQVAGVNHGIWLNRFRYNGGNAYPLLDKWIEEKSKDWKPENPFNDQLSPAAIDMYRFYGVMPIGDTVRNSSWRYHRDLETKKKWYGEPWGGADSEIGWKWYQDTLGKVTEITKKVAKFIKENPSVRLSDLGSVLGKDLSEKQFVLEVEKILDPERKSGEQHIPFIDALLNDNKARFVVNIPNKGIIHGIDDDVVVEVPALVDKNGIHPEKIEPPLPDRVVKYYLRPRIMRMEMALEAFLTGDIRIIKELLYRDPRTKSDEQVEKVIEEILALPENEEMRKHYLKR

aglA

Alpha-glucosidase

480 amino acids

Is able to hydrolyze diverse types of alpha-glycoside bonds in di- and trisaccharides: alpha-1,4 bonds of maltose and maltotriose, alpha-1,1 bonds of trehalose, alpha-1,2 bonds of sucrose, alpha-1,3 bonds of turanose and melizitose, alpha-1,6 bonds of isomaltose and melibiose. AglA is not specific with respect to the configuration at the C-4 position of its substrates because it also possesses alpha-galactosidase activity. Acts on the substrate from the non-reducing end of the chain. The activity of AglA drops with increasing length of the saccharide chain. Does not hydrolyze alpha-, beta-, and gamma-cyclodextrins or polysaccharides (starch, pullulan, amylose, amylopectin, glycogen). Does not cleave beta-glycosidic bonds in di-, oligo-, or polysaccharides.

Belongs to the glycosyl hydrolase 4 family.

54.901 kDa

MPAVKIGIIGAGSAVFSLRLVSDLCKTPGLSGSTVTLMDIDEERLDAVLTIAKKYVEEVGADLKFEKTTSVDEAIADADFVINTAMVGGHTYLEKVRRISEKYGYYRGIDAQEFNMVSDYYTFSNYNQLKYFVDIARKIERLSPKAWYSAAANPVFEGTTLVTRTVPIKAVGFCHGHYGVMEIIEKLGLERKQVDWQVAGVNHGIWLNRFRYNGEDAYPLLPRWISEKSKDWKPENPFNDQLSPAAIDMYKFYGVMPIGDTVRNASWRYHRDLETKKRWYGEPWGGADSEIGWKWYQDTLGKVTDITKKVAKFIKENPALKLSDLGSVLGKDLSEKQFVLEVEKILDPEKKSGEQHISFHDALLNDNRSRFVINIPNKGIIQGIDDDVVVEVPAVVDRDGIHPEKIDPPLPERVVKYYLRPRIMRMEMALEAFLTGDIRIIKEVLYRDPRTKSDEQVEKVIEEILSLPENEEMRKNYLKK