Protein
Methyltransferase afvD
Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Function
Methyltransferase; part of the gene cluster that mediates the biosynthesis of aflavarin, a bicoumarin that exhibits anti-insectan activity against the fungivorous beetle C.hemipterus (Ref.2, PubMed:26209694).
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily.
Sequence
MQESLTSGSSASLNIHDKRFAALYELGGKITELFAKELISQSGLPWSSQEPLVVLDNACGTGAVSSVLHHTIGNDKKANWHLTCGDKSEDMLHYTRQKMLQEEWHNAEVKIVNAQDTRLPSAHFTHIFTAFAIWVCTLSAAITNLSGDLPAPSEKEIHGVYNVGWDEEASVRAKFEQAGFNDIKVRKVIKEYLVPVNQFVESCTILIPTIVNIFWTQDQRDQYESELPMAVHRYVEGKYGRDGMASMEAEAIIATGHKH