afsK

Gene

afsK

Protein

Serine/threonine-protein kinase AfsK

Organism

Streptomyces griseus

Length

807 amino acids

Function

Component of the AfsK/AfsR system involved in the response of aerial mycelium formation to glucose.

Similarity

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Mass

85.232 kDa

Sequence

MVEQLTQHDPRRIGPFEVLGRLGAGGMGLVYLARSASGRRVAIKTVRTELAEDQLFRVRFTREVEAARAVSGFYTAAVVDADPRAAVPWLATAYVPAPSLEEIVNECGPMPTQAVRWLAAGIAQALQSIHGAGLVHRDLKPSNVLVVEDGPRVIDFGIASGVSNTRLTMTNVAVGTPAYMSPEQARDSRSVTGASDIFSLGSTLVFAATGHAPFHGANPVETVFMLVREGPDLEGLPDDLRPLIESCMQMDATHPAAEPRDLQAQLAPHLFASGSDDSGTASAWLPVPATAMIERRRGGRRTARRPPRPRPRRLRAAPQGPGAGHRLAQRGRPAFALPAVLALAAVRRVRTAAGPSAAPDGGPVQLPGAKVPIGPGRRAGEGRGAAAAAPRRRDRLGPAARRSERFLGGHGPHRTVPASTLRPGTPSPAPDRWRPWRFRMSNDVWGTPVVSGDLLYVTSFEVHALDVGNGRRQFKTRDVAWAMAVEGGRIHASDGPSLYALDAASGAEQWRLATDAWVYALKADRGTVLTATRGGGVQGWEASNGEKLWEVTGAQSDFETAEAGPVIHDGTVYLWQDARLRALDARTGLERWSYPIGDAASCGGVPVRVTPATDGYVYVAAGTRVLAVETGSGPVRWHFEAPAVFLSPPAFAPGPAVTGGGVYLADYLGTVYALDATTGKDRWRIATEARSSIEPVLVAVGNVHVGSGSALYTLDAVTDTPKWRFAAGGDVVGAPWWRRPGPLRLGGPRALHPGRGGRPAALKLATGGEITGSPVAQAGVVYACSKDRCVYALDALKGTGTGNRART

Protein

Serine/threonine-protein kinase AfsK: afsK

Gene

afsK

Protein

Serine/threonine-protein kinase AfsK

Organism

Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

Length

799 amino acids

Function

Involved in the regulation of secondary metabolism by phosphorylating, on both Ser and Thr, the AfsR global regulatory protein involved in the control of secondary metabolism.

Similarity

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Mass

83.788 kDa

Sequence

MVDQLTQHDPRRIGPFEVLGRLGAGGMGLVYLARSASGRRVAIKTVRTELAEDQLFRVRFTREVEAARAVSGFYTAAVVDADPRAAVPWLATAYVPAPSLEEIVNECGPMPAQAVRWLAAGVAEALQSIHGAGLVHRDLKPSNVLVVEDGPRVIDFGIASGVSNTRLTMTNVAVGTPAYMSPEQAKDSRSVTGASDVFSLGSMLVFAATGHPPFHGANPVETVFMLLREGPDLEGLPDELRPLIESCMQMEATGRPNPADLQAQLAPHLFGSGSDDSGTASAWLPERAVGLIEGRRNGRPAVKPATTAGGRGHGHGPSGARAPVHAPPLPPPPAHDPVVPAPPAHVPAVPAPVGAPDGGPVRLPGAAVPIGPGPRVADMRAAAVAAPPPESALAASWSRPRPGVNGADPAVPAPAPAPPEASPAGWRPWRFRMSNDVWGTPRVAEDLVYVTSFEVHALDVATGRRRFKTRDVAWSMAVADGRIHASDGPTLFALDAREGADLWRVQTDAWVYSLQADRGTVLTATRGGGVQAWEASAGQKLWEVTGAQTDFESPEAGAALHDGTAYVWQDARLRALDARTGDERWSYPIGDAASCGGVPVRLTQAPDGYVYVAAGTRVLALEVASGHVRWHFEAPAVFLAPPTFVPGPAVTGGGVYLADYLGTVYALDATDGRDRWRIATEARSSTDPVLVAAGHVHVGSGKGLYTLDAVTGTPKWRFQAGGDIVGAPAVAEGRIHFGSSDHLLYTLKADDGRLRWKLATGGEITGSPVVRDGIVYACSKDRCVYALDAEKGTGTARTT

Protein

Serine/threonine-protein kinase AfsK: afsK