Protein
Asperfuranone cluster transcription factor afoA
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Function
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of asperfuranone, a probable antitumor agent (PubMed:19199437).
Sequence
MACPTRRGRQQPGFACEECRRRKARCDRVRPKCGFCTENELQCVFVDKRQQRGPIKGQITSMQSQLATLRWQLDRYLRHRPPPSITMAGELDEPPADIQTMLDDFDVQVAALKQDATATTTMSTSTALMPAPAISSKDAAPAGAGLSWPDPTWLDRQWQDVSSTSLVPPSDLTVSSATTLTDPLSFDLLNETPPPPSTTTTTSTTRRDSCTKVMLTDLIRAELDQLYFDRVHAFCPIIHRRRYFARVARDSHTPAQACLQFAMRTLAAAMSAHCHLSEHLYAETKALLETHSQTPATPRDKVPLEHIQAWLLLSHYELLRIGVHQAMLTAGRAFRLVQMARLSELDAGSDRQLSPPSSSPPSSLTLSPSGENAENFVDAEEGRRTFWLAYCFDRLLCLQNEWPLTLQEEMILTRLPSLEHNYQNNLPARTPFLTEAMAQTGQSTMSPFAECIIMATLHGRCMTHRRFYANSNSTASGSEFESGAATRDFCIRQNWLSNAVDRRVQMLQQVSSPAVDSDPMLLFTQTLGYRATMHLSDTVQQVSWRALASSPVDQQLLSPGATMSLSAAAYHQMASHAAGEIVRLAKAVPSLSPFKAHPFLPDTLACAATFLSTGSPDPTGGEGVQHLLRVLSELRDTHSLARDYLQGLSVQTQDEDHRQDTRWYCT