Protein
Afimbrial adhesin AFA-I
Function
Hemagglutinins of uropathogenic E.coli mediate adherence to the upper urinary tract. These adhesins bind to the Dr blood group antigen and also agglutinate human erythrocytes in the presence of D-mannose (mannose-resistant hemagglutination (MRHA)).
Similarity
Belongs to the Dr-adhesin family.
Sequence
MKKLAIIGATSVMMMTGTAQANFTSSGTNGKVDLTITEECRVTVESKSESFLRSGLVANRHITNLGIQSTGCGTGQRVALKLGAGSYDDTNGAHMTHENGTDKLLVSMGSATGDGTQDGGVYYINRDGNWNGQMVFIVRNDQQHLPTGKYTLNLEGGFWTK