adssl1c

Adenylosuccinate synthetase isozyme 1 C

459 amino acids

Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

Belongs to the adenylosuccinate synthetase family.

50.826 kDa

MSFSWSAKDHKSYTNPPSNPTQGLKRPRNDTGNKVTVVLGAQWGDEGKGKVVDLLATESDLVCRCQGGNNAGHTVVVEGKEYDFHLLPSGIINPKSICVIGNGVVIHLPGLFEEAENNEKKGLKGWEKRLIVSDRAHLVFDFHQVVDGIQETQRQATEGKIIGTTKKGIGPTYASKASRIGLRVCDLLGDFKEFSTKFKNLVEQYQSMYSSLTVDTESQLKKLKEYGERLRPMVRDGVYYMYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGACTGLGIPPLNIGEVYGVSKAYTTRVGIGAFPTEQLNATGELLQTRGHEVGVTTGRKRRCGWLDLVILRYAHMINGFTAIALTKLDILDVLDEIKVGMAYKINGKRIPHFPADMELLHKVEVEYETFPGWKSDTSAARKWNNLPQKAQNYIRFVESHIGVPIKWVGVGKSRECMIQMF