adssl1a

Adenylosuccinate synthetase isozyme 1 A

449 amino acids

Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

Belongs to the adenylosuccinate synthetase family.

49.637 kDa

MSHKSCYTNPGTGGKRPRNDKGNKVTVVLGAQWGDEGKGKVVDLLATESDIICRCQGGNNAGHTVVVDGMEYDFHLLPSGIINSKAVSVIGNGVVIHLPGLLEEAEKNEKKGLKDWEKRLIISDRAHIVFDFHQAVDGLQEVQRQAQDGKNIGTTKKGIGPTYSSKASRTGLRICDLLDDFKEFSTRFKNLAQQYQAMFPTLVVDVEGQLKKLKEYAERIRPMVRDGVYFMYDAINGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPLNIGDVYGVVKAYTTRVGIGAFPTEQLNEVGELLQTRGHEVGVTTGRKRRCGWLDLVILRYANMINGFTAFALTKLDILDVMDEIKVGVSYKLKGKKIPYFPANMDVLQKVEVEYEKLPGWKSDTSACRKWEDLPVKAQNYVRFVENHVGVPIKWVGVGKARESMIQMF