adss-a

Adenylosuccinate synthetase isozyme 2 A

457 amino acids

Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

Belongs to the adenylosuccinate synthetase family.

50.016 kDa

MSAENGSPGLPNGGVCCATDSGRCSLVGNKVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINQNAIAFIGNGVVIHLPGLFEEAEKNLKKGQGLVGWEKRLCISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFSEFSQRFKLLAKQYKSMYPSLEIDIDGELKKLQDYADRVKPMVKDGVYYLYEALHGPPKNILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQSVGDVYGVVKAYTTRVGIGAFPTEQNNDTGEMLQTRGHEYGVTTGRKRRCGWLDLVLLRYAHMINGFTALALTKLDILDVLSEIKVGVSYKIDGKKIPHFPANQEVLNRVEVEYETLPGWNTDTCNVRTFEELPENAKKYVRYIELELGIPIKWIGVGKSRESMIQLF