adsl-1

Adenylosuccinate lyase

478 amino acids

Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

53.68 kDa

MAAEDKFESVLSTRYCKNSPLVSILSETNKATLWRQLWIWLGEAEKELGLKQVTQEAIDEMKSQRDNFDWSFIRAEERKLKHDVMAHNHAFGKICPTAAGIIHLGATSCYVQDNADLIAYRDSIDHILKRFATVIDRLAQFSLNNKEVVTVGRTHYQTASLVTVGKRGVLWAQELLMAFQSLAEFRDKMRFRGIKGATGTQDSFLTLFSGDEEKVEALDELVTKKANFANRFLITGQTYSRQQDSQLVFSLSLLGAAAKKVCTDIRVLQAFGELLEPFEKDQIGSSAMPYKKNPMKSERCCALARKLINAPQEALTILADQGLERTLDDSAGRRMLIPDVLLTAEALLTTLQNIFEGLTVQTDNVKKIVEDEIAFLGLEKAMMMLTEEGVDRQQAHAVIRKTALEAKQLQATQKVDIRQTMADPFFDSVRDRIVGLVNNPINFTGRCVSQTENFIAKELKPTISKYLDQSAAKVQLDV

adsl-1

Adenylosuccinate lyase

478 amino acids

Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

53.569 kDa

MASEDKFESVLSTRYCKNSPLVSILSETNKATLWRQLWIWLAEAEKELGLKQVTQDAIDEMKSNRDVFDWPFIRSEERKLKHDVMAHNHAFGKLCPTAAGIIHLGATSCFVQDNADLIAYRDSIDHILKRFATVIDRLAAFSLKNKEVVTVGRTHYQTASLVTVGKRGVLWAQELLMAFQSLSEFRDKMRFRGIKGATGTQDSFLTLFAGDESKVEALDELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLGAAAKKVCTDIRVLQAFGELLEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINAPQEALTILADQGLERTLDDSAGRRMLIPDVLLTAEALLTTLQNIFEGLSVQTDNVKKIVEDEIAFLGLEKAMMMLTEEGVDRQQAHAVIRKTALEAKQLQATQKVDIRQTMADPFFDSVRDRVVGLVNNPINFTGRCVSQTESFIAKELKPTIDKYLDKSAGNVQLDV