ade3

Trifunctional purine biosynthetic protein adenosine-3

1364 amino acids

Trifunctional enzyme required for de novo purine biosynthesis.

In the C-terminal section; belongs to the GART family.

145.663 kDa

MSHSVLVIGSGGREHAICWKLSQSTLVKQIYALPGSFGIQQVEKCRNLDAKVLDPKDFEAIAKWSKKNEISLVVVGPEDPLALGLGDVLQKEGIPCFGPGKQGAQIEADKKWAKDFMLRHGIPTARYESFTDTNKAKAFIRSAPYQALVVKAAGLAAGKGVVVAANVDEACQAVDEILGDLKYGQAGATLVVEELLEGEEISVLAFTDGKSVRAMLPAQDHKRLGNGDTGPNTGGMGAYCPCPLISQPALELVQRAVLERAVQGLIKERITYQGVLYAGLMLTRDGPRVLEFNCRFGDPETQVILPLLETDLFEVMQACCSGQLDRLPLQWRSGVSAVGVVLASAGYPETSTKGCLITGLPDVNSPTQLIFHSGLSVNKQKEALTNGGRVLIAIALDASLKEAAAKATKLAGTITFAGTGAQYRTDIAQKAFKIAIATAPGLSYKDSGVDIDAGDALVQRIKPLSRGTQRPGVLGGLGGFGGLFRLKDLSYKEPVIAEATQGVGAKIQLALQNELYENIGYDLFAMSANDLLELGAEPVAFLDYIACGKLHVPLAAQLVKGMADGCRDAKCALVGGETAEMPSLYAPGQHDMAGYCVGIVEQARVLPRFDLYEPEDLLVGLPSSGLHCAGFNEILTQLAASKVNLKECSPVGGGKHGLSLAQVLGTPTRLYVQQLLPHLQAGNQIKAVAHVTHGLLHDVQRLLPEGFEVTLDFGAVPVPDVFGWLAGQLQLSAQTLLERHNCGIGMVLVLPQSSLLWRTALPGAKVLGVLNRQAKASGGAPRVKVRNFVEQLQKLAAPFGGLGETQLPEEVKDVPSSGVKATTREECFENAVGRRLTRVPNHYVDPILILGTDGVGTKLKIAQQTHRNASVGIDLVAMCVNDILCNGAEPFSFSSYYACGKWQAALAAEVNAGVQEGASQANSSFVASHSAALPLLYEPQVYDLAGFALGIAERSGILPRLDEIQPGDVLIGLPSSGVHSNGFSLVHAVLKRAGLGLNDRAPFSEKTLGEELLVPTKIYVKALSALLSRPNHGIKALAHITGGGLSENIPRVLRKELAVRLDANKYPLPPVFAWLAAAGNISSTELQRTYNCGLGLVLVVGATEVDGVLRELRYPQRASVVGEVVARKDPKKPQVVVQNFEASLARTQRMLSQPRKRVAVLISGKGSNLQALIDAIRDSAQGVYAEIVLVISNKAGVLGLERAAKAGIPSMVISHKDFPSREVYDVELTRHLKTARVEFICLAGFMRILSVPFVREWRGRLINIHPSLLPKFPGLHVQKQALEAGETESGCTVHYVDEGVDTGAIIVQAAVPILPGDDEETLTQRIHYAEHWAFPRALALLASGALRRVSEVKKEAPKDIKDSQ

ade3

Probable phosphoribosylformylglycinamidine synthase

1323 amino acids

Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity).

In the N-terminal section; belongs to the FGAMS family.

144.867 kDa

MLVYYGGSALSVQSKKKILELTVSGVSDLNAVYFYLIYTKSNSSLNCESLRPILSDLQESEFKPDGTTMVYVFPRPGTISPWSSKATNIANVCGYKDVIRIERGIAYSVVFKDDISEEMLKSALNHLYDRMTEALRFKLPEEDEVFDKHEPAPLVRIELNCGQGGDKQAATERLNHANKKFGLALAPDEIDYLVECYTSEPSLKSREPTDVELFMFGQVNSEHCRHKIFNADWTIDGEKKDYSLFKMIRNTHLKNPQYTISAYSDNAAVFEGNSGTLFAPVNGIWSMKDEPVEFLGKVETHNHPTAVSPFPGAATGSGGEIRDEGAVGQGSLSKAGLAGYSVSDLNIPGYKQPWELDVGKPYHIATSLDIMLEAPIGSSAFNNEFGRPCINGYFRTFCMEVPRGDGTLEIRGYHKPIMAAGGIGRIRKQHAFKKSIAPGSPIIVLGGPALLVGLGGGAASSMNAGEGSEELDFASVQRGNPEMQRRAQMVIDACTTMDENIIQSIHDVGAGGVSNALPELVHDAGLGARFELRDIPCIEPSMSPMQIWCCESQERYVLSVKSEDLDTFKSICERERCPYGVVGYSTVEQRLILTDRLYNTTPIDLPMEVLFGKPPKMSRVAETQTIPLSKFDSSLKSYLAPSSDPILDAVERVLRMPAVASKSFLITIGDRSVTGLIARDQMVGPWQVPVADVGVTVTSYGKGINTGEALAMGEKPISALVSAAASARMAVAECIMNLVAASIPALDRIRLSANWMAAPSHPGEGAKLYEAVQAIGLELCPSLGISIPVGKDSMSMSMKWNEDGREKSVTAPLSLIITGFSPVDDLYSIWTPQLRKVEDIGSTSLIFIDLANGKQRLGGSILAQSYKQLGDEVPDLDNLDTFKNFINVITQLHKTNYIQAYHDKSDGGLFVTLSEMAFAGHVGIECELDSLSSDNIAALFNEELGAVIQVCDRDIAKVLELFAANGLSTCVHRIGKVLSGQAQTISFSRSGKIIFKSTRSKLHGIWHETSYKMQEIRDNPECARQEMENIADNNDPGLGYHLTFDPNVSVTADLALTSRPKVAILREQGVNGYLEMAYAFYASGFTAVDVHMTDILSGRVHLDDFVGIAACGGFSYGDVLGSGNGWATSILLHEDARNEFYRFFNERKDTFGLGICNGCQLFSRLKSLIPGAKSWPMFTFNESAQYEGRAVMLKIDETSGSKSIFTESMAGSSLPVVVAHGEGRAVFDSESDYEQFKKEGLDLIYYVNNYNERTSRYPFNPNGSRDAIAGVRSPCGRFLAMMPHPERVVLKVANSYYPHSKASEWGVHGPWIRLFQSARKWVG

ADE3

C-1-tetrahydrofolate synthase, cytoplasmic

946 amino acids

In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.

102.205 kDa

MAGQVLDGKACAQQFRSNIANEIKSIQGHVPGFAPNLAIIQVGNRPDSATYVRMKRKAAEEAGIVANFIHLDESATEFEVLRYVDQLNEDPHTHGIIVQLPLPAHLDEDRITSRVLAEKDVDGFGPTNIGELNKKNGHPFFLPCTPKGIIELLHKANVTIEGSRSVVIGRSDIVGSPVAELLKSLNSTVTITHSKTRDIASYLHDADIVVVAIGQPEFVKGEWFKPRDGTSSDKKTVVIDVGTNYVADPSKKSGFKCVGDVEFNEAIKYVHLITPVPGGVGPMTVAMLMQNTLIAAKRQMEESSKPLQIPPLPLKLLTPVPSDIDISRAQQPKLINQLAQELGIYSHELELYGHYKAKISPKVIERLQTRQNGKYILVSGITPTPLGEGKSTTTMGLVQALTAHLGKPAIANVRQPSLGPTLGVKGGAAGGGYSQVIPMDEFNLHLTGDIHAIGAANNLLAAAIDTRMFHETTQKNDATFYNRLVPRKNGKRKFTPSMQRRLNRLGIQKTNPDDLTPEEINKFARLNIDPDTITIKRVVDINDRMLRQITIGQAPTEKNHTRVTGFDITVASELMAILALSKDLRDMKERIGRVVVAADVNRSPVTVEDVGCTGALTALLRDAIKPNLMQTLEGTPVLVHAGPFANISIGASSVIADRVALKLVGTEPEAKTEAGYVVTEAGFDFTMGGERFFNIKCRSSGLTPNAVVLVATVRALKSHGGAPDVKPGQPLPSAYTEENIEFVEKGAANMCKQIANIKQFGVPVVVAINKFETDTEGEIAAIRKAALEAGAFEAVTSNHWAEGGKGAIDLAKAVIEASNQPVDFHFLYDVNSSVEDKLTTIVQKMYGGAAIDILPEAQRKIDMYKEQGFGNLPICIAKTQYSLSHDATLKGVPTGFTFPIRDVRLSNGAGYLYALAAEIQTIPGLATYAGYMAVEVDDDGEIDGLF

ade3

Adenine deaminase 3

600 amino acids

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

64.116 kDa

MSTLTRFSVQPLSTMTRRLADVASARREPDLVIQGARVLSTYSERFLDGREVWISGGRIAAVKPAGSYRGGSAKLYDARGGIIAPGLVDPHIHIESSMVTACAYAEAALLNGTTTIFCDSHEIGNVMDVAGVEAMLEDARQAPLSIFLTVPSTVPATTPDLETAGGDLTPDKIAALFDKWPEAVALGEKMDFVPVAMGDERSHAILAAALGRGRPVSGHVYGREFVAAYAASGVTDTHEAIDRGIADDLLEAGVWIFLRGGPPTTPWHSLPQAIKTITELGASHKRVAVCTDDRDAEDLLAFGLDWVTREAVKYGMRPEEAWAMGSLHGATRFGMEGEIGGLGGGRRADLVLLSDDLTPVSTWYGGKLVVDSKKITPILDEALSKPYRYPDAAYHTVKLPKNLKLTPDLPTETVVAHTIKTELPGITLGHVTVTLEPANDWQAHFDKHDLCFVTVVERHGKSAGNVAHGLLNGFGLRQGAVASSVGHDSHNIIVAGTNAADMQVALDAIEEKQGGVCVVMDGKVTAMVPLPIAGLLSDKRVHQVADEVKALKLEWEKAGCTIAYMGFNLIPLSVIPEIRITDKGLVLVPEMVISPLFEKA

ade3

Adenine deaminase 3

595 amino acids

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

62.982 kDa

MLQPWSEIAPRLVDVAMGRKPADLVVRNGRWVNVYSGEIVPGADIAIVGGRFAYVGPDAGHTIGEGTKIVDAAGRYLVPGLCDGHMHVESGLVTVTEFARAVIPHGTTTMFVDPHEIANVLGIAGVKLMNDEAQTLPVNIFVQVPSCVPSAPGLENAGATLSAADVREALAWPNIIGLGEMMNFPGVAANDSKMVAEIAATRAAGLTVGGHYASPDLGRAFHAYAAGGPADDHEGTTVEDAIARVRQGMRSMLRLGSAWFDVAAQVKAITERGIDPRNFVLCTDDSHSGTLVSDGHMNRVVRHAISQGLKPITAIQMATLNTAQHFGLERDLGSIAPGRRADLIVTSDLTALPIEIVFVRGRLLAEKGVLVADIPAYDYPASAKNTVKLGKRLAPTDFDICAAGSSEVEVRVIGVIENQAPTKALQRRLPVECGVVQMDRASDVCQIALVERHRATGGVINAFVSGFGYDTHCAMASTVAHDSHHMIVVGTNKADMAQAANRLQEVGGGIVLIAGGRELALVELPVAGLMSDQRAEIVAEKASRLVEAMRACGCKLNNAYMQHSLLALVVIPELRISDVGLIDVTRFESTEVIVR