acuI

Acrylyl-CoA reductase AcuI

330 amino acids

Probably catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Restores acrylate resistance when expressed in an E.coli strain K12 acuI deletion.

Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily.

34.45 kDa

MFNALVVDKDEESGKTQAAVKQLSLTDLPVGEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVPGIDFAGTVENSSDERYKPGDKVVLTGWRVGEAHWGGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGFTAMLAVMALEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSLGATQIVARDEINETVKRPLESEIWAGCVDAVGGAMLARVLGQMKYGASVAAVGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYANRLRAWERIARDLPMDKLEAMIRPATLSDLPGLGADILKGQVQGRVVVDVNA

acuI

Acrylyl-CoA reductase AcuI

326 amino acids

Catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Is essential for growth with 3-hydroxypropanoate as a sole carbon source. Restores acrylate resistance when expressed in the E.coli strain K12 acuI deletion.

Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily.

34.165 kDa

MRAVLIEKSDDTQSVSVTELAEDQLPEGDVLVDVAYSTLNYKDALAITGKAPVVRRFPMVPGIDFTGTVAQSSHADFKPGDRVILNGWGVGEKHWGGLAERARVRGDWLVPLPAPLDLRQAAMIGTAGYTAMLCVLALERHGVVPGNGEIVVSGAAGGVGSVATTLLAAKGYEVAAVTGRASEAEYLRGLGAASVIDRNELTGKVRPLGQERWAGGIDVAGSTVLANMLSMMKYRGVVAACGLAAGMDLPASVAPFILRGMTLAGVDSVMCPKTDRLAAWARLASDLDPAKLEEMTTELPFSEVIETAPKFLDGTVRGRIVIPVTP

acuI

Probable acrylyl-CoA reductase AcuI

324 amino acids

Probably catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA.

Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily.

34.724 kDa

MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDEFAESRPLEKQVWAGAIDTVGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRAQAWQRLVADLPESFYTQAAKEISLSEAPNFAEAIINNQIQGRTLVKVN