aceA

Isocitrate lyase 2

766 amino acids

Involved in the persistence and virulence of Mycobacterium. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

85.32 kDa

MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADADTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFYELGVKELNGHLLYALGDSEYAAAGGWLERQGIFGLVSDAVNAWREDGQQSIDGIFDQVESRFVAAWEDDAGLMTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA

aceA

Isocitrate lyase

606 amino acids

Involved in the persistence and virulence of Mycobacterium. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

67.601 kDa

MAIMDTNTEVHTLFTQEVAATQQYFDDPRFAGIIRLYTARQVVEQRGTIPTDYTVARDAATAFYARLRELFAAGKSVTTFGPYSPGQAVSLKRMGIEAIYLGGWATSAKGSITEDPGPDLASYPLSQVPDDAAVLVRALLAADRNQQYLRLHMTEQQRAATPAYDYRPFIIADADTGHGGDSHVRNLIRRFVEIGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKACFLALVRCFYELGVKELHGHLLYALGDGEYAAASAWLDRQGILAQVSGTVNAWQENGKQSIDDLFEQVEYRLLAAWEKDAGLMTYGEAVEEMLQFGESEGELIGMSPEEWRRFVGRASLYAAREKAKELGVDPGWDCELAKTPEGYYQIRGGIQYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPEQMLAYNLSPSFNWDTTGMSDEEMKRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPVAMQRWLRPPDVRRQPRPWAKVRPSTSILCRPRCRRSC

aceA

Isocitrate lyase

540 amino acids

Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. May be involved in the assimilation of one-carbon compounds via the isocitrate lyase-positive serine pathway.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

59.898 kDa

MAHKKTYSQLRSELLARYPVGLTKGGVSIDDIVQLRLQSPYESHLDVARAMASVMRADMAAYDRDTGKFTQSLGCWSGFHAQQMIKAVKRLRGTTKGAYVYLSGWMVAGLRNRWGHLPDQSMHEKTSVVDLIEEIYVSLRQADEVALNDLFNELKDARAKGATNKACEEIISRIDGFESHVVPIIADIDAGFGNEHATYLLAKEMIKAGACCLQIENQVSDAKQCGHQDGKVTVPREDFIEKLRACRLAFEELGVDDGVIVARTDSLGASLTQKIPVSQQAGDFASSYIKWLKTEPITDANPLSEGELAIWQSGNFARPIRMPNGLFSFREGTGRARVIEDCIASLKDGDADLIWIETDTPNVDEIASMVAEIRKQVPDAKLVYNNSPSFNWTLNLRKQVRAQWISEGKIAEADYPDGTALMSAQYDTSELGREADDRLRQFQVDISARAGVFHNLITLPTFHLTAKSTDELSHGYFGEDRMLAYVATVQREEIRRSISAVRHQHEVGSDLGDTFKEMVSGDRALKAGGAHNTMNQFAAE

aceA

Undecaprenyl-phosphate glucose phosphotransferase

532 amino acids

Involved in the biosynthesis of the exopolysaccharide acetan, a water-soluble polysaccharide involved in production of bacterial cellulose (BC).

Belongs to the bacterial sugar transferase family.

60.276 kDa

MGIISHSIVQCGKWQAGPARRQVVFRVHRRCFKMSEALRHLKNGETDLSSLPSGLDSIPRRIHTARGVDDSFSYRHPVLPQVVVLSDAFCVCLAVVACIAWQRIYDTPDELSGALLLANIMAAGAFFLFPKNVPLLDIPDITKVSVQIRYLLPPVAFGEVVFCTVLVMLSWPFGVTVRMGMEWLTFVVAILFVERCVGTYILHTPTMTRRLARKVAIIGSGSEATQMATRINTRMQRMFRLVGTFDDQGGDSDGTVEELVLRAREDHIDAVIICFPPACGQQHVMDVLWRLRGVLADVYVVPSLMTEDCHGWPVERFGPFSLTVLQRRPLSEWDMLEKRAFDLTASVLLLLALAPLLTLVALAIKLDSRGPVLFCQPRQGFNNRYFNVFKFRSMYTDMSDLDAARQTSRTDPRVTRIGRWIRRLSIDELPQLFNVLRGEMSLVGPRPHAPQTRAGGQLLHEAMEEYVARHRVQPGITGWAQINGSRGELVTRDDLCRRVVLDLEYIRAWSIWLDIKIIFLTIKREIFSRNAF

aceA

Isocitrate lyase

434 amino acids

Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

47.522 kDa

MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECTLAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLAASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEAGFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARLAADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRGLAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKDGYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF

aceA

Isocitrate lyase

434 amino acids

Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

47.522 kDa

MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECTLAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLAASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEAGFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARLAADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRGLAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKDGYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF

aceA

Isocitrate lyase

432 amino acids

Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

47.228 kDa

MSNVGKPRTAQEIQQDWDTNPRWNGITRDYTADQVADLQGSVIEEHTLARRGSEILWDAVTQEGDGYINALGALTGNQAVQQVRAGLKAVYLSGWQVAGDANLSGHTYPDQSLYPANSVPSVVRRINNALLRSDEIARTEGDTSVDNWVVPIVADGEAGFGGALNVYELQKAMIAAGAAGTHWEDQLASEKKCGHLGGKVLIPTQQHIRTLNSARLAADVANTPTVVIARTDAEAATLITSDVDERDQPFITGERTAEGYYHVKNGLEPCIARAKSYAPYADMIWMETGTPDLELAKKFAEGVRSEFPDQLLSYNCSPSFNWSAHLEADEIAKFQKELGAMGFKFQFITLAGFHSLNYGMFDLAYGYAREGMTSFVDLQNREFKAAEERGFTAVKHQREVGAGYFDQIATTVDPNSSTTALKGSTEEGQFHN

aceA

Isocitrate lyase

431 amino acids

Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

47.031 kDa

MSNVGTPRTAQEIQQDWDTNPRWNGITRDYTAEQVAELQGSVVEEHTLAKRGAEILWDAVSAEGDDYINALGALTGNQAVQQVRAGLKAVYLSGWQVAGDANLAGHTYPDQSLYPANSVPNVVRRINNALLRADEIARVEGDTSVDNWLVPIVADGEAGFGGALNVYELQKGMITAGAAGTHWEDQLASEKKCGHLGGKVLIPTQQHIRTLNSARLAADVANTPTVVIARTDAEAATLITSDVDERDRPFITGERTAEGYYHVKPGLEPCIARAKSYAPYADMIWMETGTPDLELAKKFAEGVRSEFPDQLLSYNCSPSFNWSAHLEADEIAKFQKELGAMGFKFQFITLAGFHSLNYGMFDLAYGYAREGMPAFVDLQNREFKAAEERGFTAVKHQREVGAGYFDTIATTVDPNSSTTALKGSTEEGQFH

aceA

Isocitrate lyase

427 amino acids

Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

46.783 kDa

MSGWQETAEKLEMSWSNDVRWQGVERPYSGEEVVKLRGSLKIEYTLAKTGAEKLWKLLHEEDYVNALGAMTGGQAIQQVKAGLKAIYLSGWQVAADANLAGHMYPDQSLYPANSVPSVVKRINQALQRADQIQHLEGEGEVDYFAPIVADAEAGFGGQLNVFELMKAMIEAGASGVHFEDQLASEKKCGHLGGKVLIPTQTAIRNLVSARLAADVMGVPTILVARTDADAADLITSDIDPADQRFITGERTPEGFYRTNAGIEQAIARGLAYAPYADLIWCETSKPSLEEAKQFADAIHEKFPGKLLAYNCSPSFNWEANLDRATIETFQQELGKMGYKFQFVTLAGFHALNHSMFELAYGYKQRGMGAYSELQQAEFASEVKGYTATRHQREVGTGYFDQVAQTITGGTSSTTALTGSTEEAQFQK

aceA

Isocitrate lyase

345 amino acids

Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily.

39.015 kDa

MNPTELDSDVFAQDVDNQKARELREMLNTQDFVFAPGMYHALDARLAEMTGHDAAYMSGYSTVLGQFGFPDLEMVTMTEMVENAKRMVEATNLPVIADCDTGYGGIHNVRRAVREYEKAGVAAVHIEDQTTPKRCGHIAGKQIVSREKAKARFEAAVDAKQSEDTVVIARTDAYGSSNGDWDEHVERGRIYADAGVDIVWPEMPNPSREDAVAYAEEIHETHPDLKLAFNYSSSFAWSEEEDPLTFQELGDLGYKYIFITLFGLHSGAHAVYEDFKKLAEQDEEGQFDLEQRYLDHPTESHHELSFVSRYQDIETEFDPEARRRIEESEGFSEEQADPITSNDDD

aceA

Isocitrate lyase

15 amino acids

Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.

1.71 kDa

single

MTYQTAIDAVRELKA