Protein
Bifunctional protein Aas
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Function
Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
Similarity
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
Sequence
MLFKFLRLVFRLMFRLTVEGDIKQFNHPKCLITPNHVSFLDGVLLTLFLPVKPVFAVYSNIANRGFMKLVSRYVEIVPLDPINPMAVRILVKEIEKGRPIVVFPEGRITVTGSLMKIYDGAAFIAAISEAVVVPVRFEGLERTLFSRLKGIFKLHLFPKVTMKILPATQLLMPNASSSEQRRRLAGERLHEIMMNARMATRPQETIFESLLVARKQFGRFKPCIEDVSFKEDSYNSLLKKVLAASRILQRFTCQGERIGFLLPNATIMVAAIFGASLRGRIPALLNYTTDSHGLKNALAVASIKTIVTSRQFLKKERLTHLSEQVTEVNWVYLEDLESTVTLLDKLWILWHLFFPKQAMVAQKPDDDALVLFTSGSDAVSKGVVHSHASLLANVEQIKTITDFNPLDRFMSSLPLFHAFGLTVGLFTPLLSGSRIFLYPNPLHYRVVPELVYECNCTVLLGTSSFLENYAYSAHPYDFARLRCVIAGIEKLAENTKQIWQDKFGIRILEGYGMTECAPVIALNVPMMAKVGTVGRILPAMEFRLIPIAGIKQGGRLQLRGPNMMKGYLRMEDPNHLEPPAVKDEHGNIQFDWLDTGDIVSIDEQGFCTILGRGKRFAKQGELDGGKADFVTLCKIAEAE