aarA

Gene

aarA

Protein

Protein aardvark

Organism

Dictyostelium discoideum

Length

757 amino acids

Function

Required to regulate pattern formation during multi-cellular stages of development and for the formation of adherens junctions. Plays a structural role during the regulation of stalk formation. Involved in cell signaling. Required for spore-cell differentiation. Overexpression increases number and size of cell junctions and reduces spore-cell formation.

Similarity

Belongs to the beta-catenin family.

Mass

85.924 kDa

Sequence

MNDCGSLFNKKLFKMNLLFKHLKLQQHLKLQQKPLLNNSSINNNINNNNNNNNNNNSNNDSNNTNTNIFNNSFLNSDLIERLIIKFTIGYLKNNITEDYIEQILLENQNNFIKSTTTSNYILEENNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSSSSSILSKFNKLEEDNELELQKKQKQQLEQQEEELFNQFNFLEGIEDQNDFLSEQETIQKIKFLIKMTAKSMSNYSSPNTLIPSVSKTYISPFGLSSNGSTNNHNNNNNNNHHHHSNNGNLIESSNNVNNQLNVSNYNNNNSNHYDENNQFDIFLIPTEMLVHLLSFLSANDLWRISLTCKRIWYIVDVFKFWELLFEQTCPRIYYAMQFNSRWSNPTSFQSKMILCYIDRLPTDNYKNFDKSDESGQIKKIIGVMNENLHNPMILRETCYILKRLSYRQRKEDEHESLIARYGGISLILQAMKNHPYDAGVQEDACGALGNLTCDSPNNMGLYSNDNYLSVVEQGGIQLILQAMKNHMMNPGVQYNTSFVLRNLARNDVSESRVAIEGGIQSIATAMKNHPNHIGIQTQGCGALRNLGCNDSNKVLSAKEGGIGLILRAMRSFSSHPDLQLNGCGALRNLARNEDNKNMISRQNGIQLVLGAMSNHPDDPDVQDEGCAALINLAYQDEANEETIAREGGINLILKAMRNHPFHSGVQMQGRGALKNLSCNPKNKLTIARSGGIELMNIAMQNHPNFANRFLELSRILQVALEDGNI

Protein

Protein aardvark: aarA

Gene

aarA

Protein

Citrate synthase

Organism

Acetobacter aceti

Length

436 amino acids

Similarity

Belongs to the citrate synthase family.

Mass

48.197 kDa

Sequence

MSASQKEGKLSTATISVDGKSAEMPVLSGTLGPDVIDIRKLPAQLGVFTFDPGYGETAACNSKITFIDGDKGVLLHRGYPIAQLDENASYEEVIYLLLNGELPNKVQYDTFTNTLTNHTLLHEQIRNFFNGFRRDAHPMAILCGTVGALSAFYPDANDIAIPANRDLAAMRLIAKIPTIAAWAYKYTQGEAFIYPRNDLNYAENFLSMMFARMSEPYKVNPVLARAMNRILILHADHEQNASTSTVRLAGSTGANPFACIAAGIAALWGPAHGGANEAVLKMLARIGKKENIPAFIAQVKDKNSGVKLMGFGHRVYKNFDPRAKIMQQTCHEVLTELGIKDDPLLDLAVELEKIALSDDYFVQRKLYPNVDFYSGIILKAMGIPTSMFTVLFAVARTTGWVSQWKEMIEEPGQRISRPRQLYIGAPQRDYVPLAKR

Protein

Citrate synthase: aarA

Gene

aarA

Protein

Rhomboid protease AarA

Organism

Providencia stuartii

Length

281 amino acids

Function

Rhomboid serine protease that catalyzes intramembrane proteolysis. Mediates quorum-sensing and the subsequent regulation of target genes via activation of the Tat protein export system. Catalyzes the proteolytic activation of TatA by removal of its N-terminal extension.

Similarity

Belongs to the peptidase S54 family.

Mass

31.106 kDa

Sequence

MAEQQNPFSIKSKARFSLGAIALTLTLVLLNIAVYFYQIVFASPLDSRESNLILFGANIYQLSLTGDWWRYPISMMLHSNGTHLAFNCLALFVIGIGCERAYGKFKLLAIYIISGIGAALFSAYWQYYEISNSDLWTDSTVYITIGVGASGAIMGIAAASVIYLIKVVINKPNPHPVIQRRQKYQLYNLIAMIALTLINGLQSGVDNAAHIGGAIIGALISIAYILVPHKLRVANLCITVIAASLLTMMIYLYSFSTNKHLLEEREFIYQEVYTELADANQ

Protein

Rhomboid protease AarA: aarA