Protein
Zinc finger FYVE domain-containing protein 26
Organism
Ailuropoda melanoleuca
Function
Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair (By similarity).
Similarity
Belongs to the ZFYVE26 family.
Sequence
MHHPFGKEETASQKQLFGFFCECLRRGEWELAQACVPQLHEAQGDIPKKVEDILQALVVCPDQLRCGQDIDPQRLAWVWFLVLEKWFSQEKKLLPSVFRRKLEFLLLSEDLRRDIPEDILKELYEALAQDTGGPVLDGNQKRESWTPRLSSEAVSVFWDLLRQAPQLAQALLELLRTKDDSAGLSGWSLQKALVDRVRRALGAVQGPTTGPAGIVDAIYGALRSLRCPAEPLGGELRLLCEELLEACRAEGSPLQEEQVLSCLLHKAGRSLVSLYGHIYAEKATEKPAKAVHLGKVSPDHLDPEQAMLALFCNPDPSQAWKSAYFYCLSNSKHFLEQILVTALALLKEEDFPSLGCLLDREFRPLSRLLVLLGWMHCQSLASAKRLLQTLHRAQDQGCDKLLRDACDGLWAHLEVLEWCVQQSSNPIPKRDLLCHLHGGDSHSVLYSLHHLTNLPALREEDVLKLLQKVPAKDPQQEQDSAEAPVPEHLSRCQNLTLYQSFCAMKYAIYALCVNSHQHSQCQECRDSPSEDPALAAEPANDSLSSPGASDLFSTYLARCQQYLCNVPDSLCLELLENIFSLLLITSADLHPEPHLPEDYAEDEDIEGKGLLGLRSPSESPQHIAQPERKSEQGCQEVPRSLACTVPNCLKTEPKESSPGLHGHSFLDLKHFTSGISGFLADEFAIGAFFRLLQEQLDKLSSHSPPEKPKLPEGQSCSGSRDGLQSRLHRFSKVLSEAQWRYKVVTSNQGSEEQPSRRYWPIATGHPSLRRGRRTRRSRPDGRDRSSNPSLESTSSELSTSTSEGSLNAVSGRNELDGRLQPQSQNSLIPMMFSPPESLLASCILRGNFAEAHQVVFMFNLKSSPSSGELMFMERYQEVIQELSRVEHKIENQNSDGGSSTIRRTGSGRSTLQAIGSAAAAGMVFYSISDVTDKLLSTSGEPIPTLQEDFWISNTLVEPTAPLREVLEDLSPPAMAAFDLACSQCQLWKTCKQLLETAERRLNVSLESRGRRLDHILLSADGIRGFPVVLQQISKILNYPLTSAGQSKSESVEEKGAGPPRCSIAELLQMCWPSLTEDCVASHATLSQQLDQVLQVLREALQRPEPRSTPLSSLVEQAAQKAPEAEAHPVHIQTQLLQKNLGKQTPAGSRQTDYMGTFFSYCNTMAAVLLRSLSSEPDHMEVKVGNPFVLLQQSSSQLVSHLLLERQVPPDRLAALLAREGLSLSVPKVIVNCCCEPLALCSSRQSQQTSSLLTHLDVLVQLHTSHCLEDLPLSTLSSPKPTGNSTLERKPHSSPRDSSLPAFTSSALAFLKSRSKLLATVACLGASQGPKLTKPSLSWKELRGRREVPLSAEQVAQECERLLEQFPMLKASLLAAWEPLRRSTEQGQSLAVSLCGRASLSTVLLGLHSPSALDVLTEAFEEALVARDWSRALQLTEVYGRDVDDLSNIKDAVLSCATACDKEGWRFLFPVKDASLRSRLTLQFVDRWPLEWCLEILAYCISDTAVQGGLKCELQRKLAELRVYQKILGLQATPVWCDWQSLRNCCIEDPSAVMNMILEAKEYGLCEEWGCLYPIPREHLISLHQKHLLHLLERGDHEKALQLLRKIPDPTMCLEVTEQSLDQHPSLAASHFLANYLTTHFYGELTAVRHHEIQALYMGSKVLLTLPEPHRASYSHLSSNPLLMLEQLLMNMKVDWATVAVQTLHQLLAGQEIGFTMDDIDSLLSIYAGKALDFPYSLREKRSDSLTHLQEVSQPSDLVTLSRSPSGEFSVAAAVAAPGVSTIHSPSPRERSFPESQPPPEFVPPATPPGRPQWVPDESASICMVCCRERFTMFNRRHHCRRCGRLVCSACSTKKMVVEGCRESPTRVCDQCYSYYNKDVPEENAGQPEAPDSSKSESPPYSAVVRVPKAAEVEWILDLNEEENELVRSEFYYEQSPSASLCIAILNLHRDSIACGHQLIEHCCRLSQGLTNPEVDAGLLTDIMKQLLFSAKMMFVKAGRSQDLALCDSYISKVDVLNILVAASYRHVPPLDQILQPAAVTRLRNQLLEAEYYQLGVEISTKTGLDPTGAWHAWGMACLKAGNLTAAREKFGRCLKPPFDLNQLSHGSRLVQDVVEYLESTVRPLLSLQDDDYFATLKELEATLRTQSLSLEVIPEGKIMNNTYYQECLFYLHNYSTNLAIISFYMRHSCMREALLHLLNKESPPEVFIEGIFQPSYKSGKLHTLENLLESIDPTLETWGKYLIAACQHLQKKNYYHILYELQQFMKDQVRAAMTCIRFFSHKAKTYTELGEKLSWLLKAKDHLKIYLQDTSRSTRRKKTTFFQKKMTAADVSRHMNTLQLQMEVTRFLHRCESAGTSQITTLPLPTLFGNNHMKMDVACKVMLGGKNVEDGFGIAFRVLQDFQLDAAATYCRAARQLVEREKYSEIQQLLKCVSESGMAATSDGDTILLNCLEAFKRIPPQELEGLIQAIHSDDNKVQAYLTCCKLRSAYLIAVKQEHSRATVLVQQVQQAAKSSGDAVVQDICAQWLLTSHTRGSHGSGSRK