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ZPR1

Gene
ZPR1
Protein
Zinc finger protein ZPR1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
486 amino acids
Similarity
Belongs to the ZPR1 family.
Mass
55.072 kDa
Sequence
MSEQKEDLFKPVGEAAAEVEDESIAEQNKANDGVKLTGAQDAMGHPVQEIESLCMNCGKNGTTRLLLTSIPYFREIIIMSFDCPHCGFKNCEIQPASQIQEKGSRYVLKVECREDFNRQVIKSETATCKFVELDIEIPAKRGQLTTVEGLLSEMIDDLSQDQEMRKSIDEALYKKIDDFIQKVKSYINCEPNTIPITFILDDPAGNSWIEYKPGEPQHKWSHTQYVRTDEQNVQVGIITRDQLEQRRQEQLKQLANRERNPSESVKVGSANPQFLSDATDIENFNNEVQTFRASCPSCTQECETHMKPVNIPHFKEVIIMSTVCDHCGYKSNEVKTGGAIPDKGRRITLYCDDAADLSRDILKSETCSMVIPELHLDIQEGTLGGRFTTLEGLLRQVYEELESRIFTQTSDSMDEATKARWVEFFAKLKEAIAGKVKFTVIMEDPLAGSYIQNVYAPDPDPNMTIEDYERTKEQNEDLGLSDIKVE

Gene
zpr1
Protein
Zinc finger protein ZPR1 homolog
Organism
Dictyostelium discoideum
Length
477 amino acids
Similarity
Belongs to the ZPR1 family.
Mass
53.55 kDa
Sequence
MSEEIINKKLENTKIEEKEEEFKNISHENEVTEIESYCVNCEAENGITRILLTKVPFFKEIMVFAFHCPECGFRSSEVRSGGSYELKGCHIELNVTKELDLNRQIVKMEKATISIPSLDFEIPPSNNGSLNTIEGIIKEAITNLTNASEIHTESKEELLGFVSKLSNLLMVDEPFKIIVDDPSGNSFIENPNAPKADTNLKVTNYTRTAEQNASLGLGINEEQQKQQQEDSKKNERVTTTSVSIPSGDLADREVYSLPNQCSYCGVMGECKMVLTDIPYFKSILLMAFSCDECGYKTNEIKPGGAISEKGKTITLRVESVEDLSRDILKSDTANVIIPELEIEVTHGSLGGKFTTVEGLITIIKEELEKNPFFRGDSSDPANRARYQEITSQLDSFIAGKKPFTIELDDPISNSYIQNLFAPDDDPQLKIVEYERTYEQNDELGLNAMNTENYLNNQEENDNEAENEKSEEKESDSK

Gene
ZPR1
Protein
Zinc finger protein ZPR1
Organism
Homo sapiens
Length
459 amino acids
Function
Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death.
Similarity
Belongs to the ZPR1 family.
Mass
50.925 kDa
Sequence
MAASGAVEPGPPGAAVAPSPAPAPPPAPDHLFRPISAEDEEQQPTEIESLCMNCYCNGMTRLLLTKIPFFREIIVSSFSCEHCGWNNTEIQSAGRIQDQGVRYTLSVRALEDMNREVVKTDSAATRIPELDFEIPAFSQKGALTTVEGLITRAISGLEQDQPARRANKDATAERIDEFIVKLKELKQVASPFTLIIDDPSGNSFVENPHAPQKDDALVITHYNRTRQQEEMLGLQEEAPAEKPEEEDLRNEVLQFSTNCPECNAPAQTNMKLVQIPHFKEVIIMATNCENCGHRTNEVKSGGAVEPLGTRITLHITDASDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLGDSSNPGQTERLQEFSQKMDQIIEGNMKAHFIMDDPAGNSYLQNVYAPEDDPEMKVERYKRTFDQNEELGLNDMKTEGYEAGLAPQR

Gene
Zpr1
Protein
Zinc finger protein ZPR1
Organism
Mus musculus
Length
459 amino acids
Function
Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death.
Similarity
Belongs to the ZPR1 family.
Mass
50.715 kDa
Sequence
MSASGAVQPGHPGAAVGPSPAAAASPATGPLFRPLSAEDEEQQPTEIESLCMNCYRNGTTRLLLTKIPFFREIIVSSFSCEHCGWNNTEIQSAGRIQDQGVRYTLTVRSQEDMNREVVKTDSATTRIPELDFEIPAFSQKGALTTVEGLISRAISGLEQDQPTRRAVEGAIAERIDEFIGKLKDLKQMASPFTLVIDDPSGNSFVENPHAPQKDNALVITYYDRTPQQAEMLGLQAEAPEEKAEEEDLRNEVLQFNTNCPECNAPAQTNMKLVQIPHFKEVIIMATNCENCGHRTNEVKSGGAVEPLGTRITLHITDPSDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLGDSSNPDQSEKLQEFSQKLGQIIEGKMKAHFIMNDPAGNSYLQNVYAPEDDPEMKVERYKRTFDQNEELGLNDMKTEGYEAGLAPQR

Gene
zpr1
Protein
Zinc finger protein zpr1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
459 amino acids
Similarity
Belongs to the ZPR1 family.
Mass
51.377 kDa
Sequence
MAEEKKEELFTSIGNAAQNVSTAEDREGNGVQEVESLCMECGKNGTTKLLLTVIPYFREVVLMSFECPHCGFKNAQVQHAETIQPEGSKITFHVEDKEDLNRTVVKSQEAIVSIPEIQLEIPGRLGQLTTIEGILSNVVDDLSKEQESRKESAPQLYDQINAFIEKVNSLRSGSVPFTITVDDITGNSWIEMKPGRDGDRWSQVSYKRTLEQNTKLGLVDTDQPEDVKTQTNNASNTLKHDATAVEVDPNEVHTFHATCPSCSHQCDTHMKLLDIPHFKEVIIMSTVCDRCGYRSNEVKTGGEIPPKGRKITLKVMDAEDLSRDILKSETASLKIPELGLDLFPGTLGGRFTTIEGLLAQVYDELYGRVFSQETDSMTPEQVANWQQFLCNLTAAREGATQFTLILDDPLSQSYLQNYYAPDPDPNMTIEEYERSFQVNEELGLNDMKTENYEKDGGKK

Gene
ZPR1
Protein
Protein LITTLE ZIPPER 1
Organism
Arabidopsis thaliana
Length
136 amino acids
Function
Competitive inhibitor of the HD-ZIPIII transcription factors in shoot apical meristem (SAM) development. Acts by forming non-functional heterodimers. Part of a negative feedback loop. Essential for proper functioning of stem cells in the SAM.
Mass
16.255 kDa
Sequence
MQREHKTHNKLSFIYITPLYISPINQTRLTYLSSSFLLSSSSKMCLSSSETFSDTPTRLVLYLKTQSHVRIPRLSRRRRMWREEKKMEMINLKLYVENQNIIRENEKLKKKALLLHQENKTLFSLLQTKKLSSVHK