Zc3h3

Zinc finger CCCH domain-containing protein 3

950 amino acids

Required for the export of polyadenylated mRNAs from the nucleus (By similarity). Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage (PubMed:16115198).

103.224 kDa

MEEKEQLRRQIRLLQGLIDDYKTLHGNGPALGNSSATRWQPPMFPGGRTFGARYSRPSRRGFSSHHGPSWRKKYSLVNQPVESSDPASDPAFQTSLRSEDSQHPEPQQYVLERQVQLSPDQNMVIKIKPPSKSGAINASGVQRGSLEGCDDPSWSGQRPQGSEVEVPGGQLQPARPGRTKVGYSVDDPLLVCQKEPGKPRVVKSVGRVSDSSPEHRRTVSENEVALRVHFPSVLPHHTAVALGRKVGPHSTSYSEQFIGDQRANTGHSDQPASLGPVVASVRPATARQVREASLLVSCRTSKFRKNNYKWVAASEKSPRVARRALSPRTTLESGNKATLGTVGKTEKPQPKVDPEVRPEKLATPSKPGLSPSKYKWKASSPSASSSSSFRWQSEAGSKDHTSQLSPVPSRPTSGDRPAGGPSSLKPLFGESQLSAYKVKSRTKIIRRRGNTSIPGDKKNSPTTATTSKNHLTQRRRQALRGKNSPVLRKTPHKGLMQVNRHRLCCLPSSRTHLSTKEASSVHMGIPPSNKVIKTRYRIVKKTPSSSFGAPSFPSSLPSWRARRIPLSRSLVLNRLRPAITGGGKAPPGTPRWRNKGYRCIGGVLYKVSANKLSKTSSRPSDGNRTLLRTGRLDPATTCSRSLASRAIQRSLAIIRQAKQKKEKKREYCMYYNRFGRCNRGECCPYIHDPEKVAVCTRFVRGTCKKTDGSCPFSHHVSKEKMPVCSYFLKGICSNSNCPYSHVYVSRKAEVCSDFLKGYCPLGAKCKKKHTLLCPDFARRGICPRGSQCQLLHRNQKRHGRRTAAPPIPGPSDGAPRSKASAGHVLRKPTTTQRSVRQMSSGLASGAEAPASPPPSPRVLASTSTLSSKATAASSPSPSPSTSSPAPSLEQEEAVSGTGSGTGSSGLCKLPSFISLHSSPSPGGQTETGPQAPRSPRTKDSGKPLHIKPRL

ZC3H3

Zinc finger CCCH domain-containing protein 3

948 amino acids

Required for the export of polyadenylated mRNAs from the nucleus (PubMed:19364924). Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage (By similarity).

101.941 kDa

MEEKEILRRQIRLLQGLIDDYKTLHGNAPAPGTPAASGWQPPTYHSGRAFSARYPRPSRRGYSSHHGPSWRKKYSLVNRPPGPSDPPADHAVRPLHGARGGQPPVPQQHVLERQVQLSQGQNVVIKVKPPSKSGSASASGAQRGSLEEFEETPWSDQRPREGEGEPPRGQLQPSRPTRARGTCSVEDPLLVCQKEPGKPRMVKSVGSVGDSPREPRRTVSESVIAVKASFPSSALPPRTGVALGRKLGSHSVASCAPQLLGDRRVDAGHTDQPVPSGSVGGPARPASGPRQAREASLVVTCRTNKFRKNNYKWVAASSKSPRVARRALSPRVAAENVCKASAGMANKVEKPQLIADPEPKPRKPATSSKPGSAPSKYKWKASSPSASSSSSFRWQSEASSKDHASQLSPVLSRSPSGDRPAVGHSGLKPLSGETPLSAYKVKSRTKIIRRRSSTSLPGDKKSGTSPAATAKSHLSLRRRQALRGKSSPVLKKTPNKGLVQVTTHRLCRLPPSRAHLPTKEASSLHAVRTAPTSKVIKTRYRIVKKTPASPLSAPPFPLSLPSWRARRLSLSRSLVLNRLRPVASGGGKAQPGSPWWRSKGYRCIGGVLYKVSANKLSKTSGQPSDAGSRPLLRTGRLDPAGSCSRSLASRAVQRSLAIIRQARQRREKRKEYCMYYNRFGRCNRGERCPYIHDPEKVAVCTRFVRGTCKKTDGTCPFSHHVSKEKMPVCSYFLKGICSNSNCPYSHVYVSRKAEVCSDFLKGYCPLGAKCKKKHTLLCPDFARRGACPRGAQCQLLHRTQKRHSRRAATSPAPGPSDATARSRVSASHGPRKPSASQRPTRQTPSSAALTAAAVAAPPHCPGGSASPSSSKASSSSSSSSSPPASLDHEAPSLQEAALAAACSNRLCKLPSFISLQSSPSPGAQPRVRAPRAPLTKDSGKPLHIKPRL

ZC3H3

Zinc finger CCCH domain-containing protein 3

597 amino acids

Required for the export of polyadenylated mRNAs from the nucleu; binds to polyadenylated mRNA, and is involved in the regulation of mRNA polyadenylation.

66.322 kDa

MLPHISADEAQPSMSRKVYINPNFQLQGQTAHQLPFQVPFQAFQAPLQPQPAIHINPHFLNRQRAMYDQYQREQQEQLMMQQVSASHYRLDPTIHLLATPPPPPAKIISKVSTCLVRKPSVVASGPAVKLAASVPVPTVSSLVQPPLVSISKRKIVRQGALKAAPAVAALHPPPPAKRTRYKLVRSISLTCTPLVKKRRPLREFVGQYALRRTNEAQPNRKLSSKPQALKLGVNKSLSMVSIHGVMYKKISKNKITKLDASSSARVAKSESPRTLQRTLSGRTLFVSGNKFILDPSGCRLTRVSTSSTGATQSSVNRSILRRIDIGGLTYVASPKALNVFVRTSNHVSRAHLITAKQRSLTLLNKSLVKTNVPCAIFQKLGKCVAHSRGKCRKLHDKRQVAICVSFLRGECTKPKCLLSHNVTLEKMPVCRYYLRGVCVREDCPYLHKKLSSKTEICIDFVRGYCPLAAECNKRHEFSCPELERKGKCELPRCVFCKKSPSKRLAKVKSRPKLGSKPVAFTDTAKESSTADELPTSSRYFGSHKEPAEAILTRDDVEQKKPEAEDEDQKEAGAPCPRRRPQLGTLPSFIPLGGEEKL